Coming into the season, who would have thought that Week 4's biggest matchup would come in Buffalo with both the New England Patriots and the Buffalo Bills sitting atop their division at 3-0. While the Patriots have faced teams with a combined record of 0-9, the Bills haven't faced anyone particularly imposing either, with there wins coming off of teams with a combined record of 1-8.

This week could possibly be the biggest game in Buffalo in years as they try to take down a team that has dominated them for the better part of two decades.

Here are three bold predictions for the Patriots in the game of the week this Sunday.

3. The Patriots will let up 2 touchdowns to Josh Allen

This might not seem bold to some, but through three games so far the Patriots defense has been nothing short of perfect. Having not let up an offensive touchdown to an opponent yet, Josh Allen will have a long day in front of him.

What gives Allen an edge over the quarterbacks the Patriots have faced so far is his ability to run. Allen will get one of his scores through the air, but also have one that he runs in. Already with two rushing scores on the season, head coach Sean McDermott is not afraid to have his 6-foot-5 franchise quarterback barrel into the end zone.

2. James White will have his breakout game 

As White was unavailable for last weeks win against the Jets due to the birth of his child, the Patriots didn't seem to miss him. This week, however, will be his opportunity to make his first big impact of the season.

The Bills host one of the stingiest defenses in the league and while they have had a player run for over 100 yards on them, that player was Saquon Barkley. With Sony Michel not expected to be in the fold too much due to Buffalo's ability to stuff the run, it gives James White the chance to make some big catches out of the backfield.

Brady and White have a strong connection and have shown their fondness of getting White little screen passes and letting the quick running back make people miss. Bill Belichick will not play to the Bills' strength and run the ball right at their tough defense. White is in a prime spot to score a couple touchdowns and catch some short yardage throws, letting his teammates block for him as he tries to stretch them out with his elusiveness.

1. Julian Edelman will play and go for over 100 yards receiving

After suffering a chest contusion last Sunday, Julian Edelman is still making the trip to Buffalo and is expected to play. Not only will be play, he will play terrific. Edelman has seemingly always been there when Brady needs him, and Sunday's matchup will be no different.

Edelman will not haul in long yardage passing plays, but will be involved in many of them, especially on third down. While Buffalo does let up the ninth-fewest passing yards per game, it's Tom Brady and he will without a doubt get his throws to his receivers. Whether it's the Super Bowl or the biggest game of the regular season so far, Edelman has always stepped up when it matters most.