The San Francisco 49ers have suffered a blow to their offense before the regular season even starts. According to Adam Schefter of ESPN, San Francisco has placed Jerick McKinnon on season-ending injured reserve.

Prior to the 2018 season, the 49ers signed McKinnon to a four-year, $30 million deal to become the team's featured running back. Nearly a week before the regular season began in 2018, McKinnon suffered a torn ACL in practice—ending his first season with his new team.

Coming into training camp, the elusive running back was placed on the physically unable to perform list. After a couple of weeks into the preseason, McKinnon was activated to the roster and returned to practice.

Sadly, the 49ers running back recently sustained a setback on his surgically repaired knee that he injured last season. After placing the running back on season-ending IR, it seems as if the setback is fairly serious.

For the second straight season, McKinnon will be incapable of making his debut for the 49ers in Week 1. Luckily for San Francisco, they have plenty of options to replace McKinnon in the backfield.

During the spring, San Francisco decided to sign running back Tevin Coleman in free agency. Of course, Coleman spent time with Kyle Shanahan before when Shanahan was the Atlanta Falcons offensive coordinator.  Therefore, there is some comfortability with Coleman in Shanahan's offense.

Aside from Coleman, the team also has Matt Breida, Jeff Wilson, and Raheem Mostert at running back; all of whom contributed for the offense in 2018.  The fans in San Francisco were eager to see McKinnon in their offense this year but a devastating injury will cost him his season again.