In the first few weeks of the 2017 NFL season, there have major injuries to arise over the league to many prominent players. The Buffalo Bills were one of the latest teams to be hit with the injury bug as tight end Charles Clay was carted off the field due to a knee injury during Sunday's 20-16 loss to the Cincinnati Bengals, according to Mike Rodak of ESPN.com.

 Buffalo Bills tight end Charles Clay, the team's leading receiver, was carted to the locker room after suffering a knee injury in the first quarter of Sunday's 20-16 loss to the Bengals.

The ailment occurred after Clay was tackled low by Bengals safety Shawn Williams after he hauled a 24-yard reception. He had stayed on the field in apparent pain prior to being taken off the field by the team's medical staff.

Clay had emerged as a dependable target in the passing game over the last three seasons with Buffalo. He is the first tight end in franchise history to record back-to-back campaigns with 50 or more receptions and 500-plus receiving yards. He also is tied for most consecutive games (three) with one or more receiving touchdowns by a tight end.

The 28-year-old had put together a strong start to the season with 18 catches on 25 targets for 227 receiving yards and two touchdowns. If Clay is sidelined for a long period of time, the Bills will likely turn to Nick O'Leary and Logan Thomas to help fill the void.