One of the premier matchups in Week 6 of the NFL puts the undefeated Arizona Cardinals against the Cleveland Browns.

Per Jake Trotter of ESPN, the Browns will have to get it done without one of their heave hitters against Arizona.

Not having Nick Chubb is huge but Kareem Hunt is the “backup” running back for the Browns and would start on most teams. However, Hunt is listed as questionable for the game against Arizona although he is expected to play.

Cleveland will need to be as healthy as possible especially on defense as they try to slow down the high-powered attack that Arizona has displayed so far this year. The Browns can be thankful that Zach Ertz, who the Cardinals just traded for on Friday, won't be playing in the game.

The Browns will try to wash out a super sour taste in their mouth after losing an instant classic against the Los Angeles Chargers a week ago. The 42 points scored by Cleveland weren't enough as they lost 47-42 to Justin Herbert and LA.

Now they get set to face another top tier offense in the Cardinals. Having Hunt available and able to start on the other side of the ball is critical for the Browns in the absence of Hunt. It's also possible Cleveland gets star wideout Jarvis Landry back, as they designated him to return from injured reserve.

Sunday's game between these two will be appointment television.