The San Jose State Spartans are set to face the San Diego State Aztecs. Check out our college basketball odds series, which includes our San Jose State San Diego State prediction, odds, and pick.

The San Jose State Spartans are just beginning the Tim Miles era. Miles is no stranger to the Mountain West Conference, as college basketball odds analysts know well. He coached five seasons at Colorado State before going to Nebraska and leading the Huskers to an NCAA Tournament appearance. Miles is widely respected in the coaching profession, and many felt that San Jose State got a steal when it convinced Miles to come to the San Francisco Bay Area to coach the Spartans. The first season for Miles in Silicon Valley has been rough, as everyone predicted, but the Spartans are showing that they can be feisty. They could have given up on their season in the face of a lot of losses, but they finally won a Mountain West game this past Sunday by upsetting New Mexico, 71-55. San Jose State won't go winless in MWC play, something to note when making a San Jose State San Diego State prediction.

The Spartans are 8-19 overall this season. No one expects them to actually beat San Diego State on the road in Viejas Arena, but the Spartans are proving that they're not a complete pushover, and that they will make opponents work hard to beat them. The San Jose State San Diego State odds aren't favorable to the Spartans, but that won't stop them from giving it the old college try and an honest effort on the court.

San Diego State wasted a massive opportunity to play its way into the 2022 NCAA Tournament earlier this week. The Aztecs led Boise State by one on the road and had Matt Bradley at the free throw line for two shots with 7.7 seconds left. Bradley then missed both free throws, and San Diego State got whistled for a questionable foul call with under two seconds remaining. Boise State made both foul shots, giving San Diego State a crushing 58-57 loss. The foul call was bad, but if SDSU had made two free throws six seconds earlier, the Aztecs would have almost certainly won. As things stand, San Diego State is still in the hunt for an NCAA Tournament berth, but a loss here would destroy those hopes. The Aztecs have to win this game and then pick up at least three more wins in the coming weeks (including the Mountain West Tournament) if they want a reasonably good shot at an at-large bid. Everyone in the San Diego State locker room knows the stakes involved in this game, a good thing to remember when considering a San Jose State San Diego State pick.

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Courtesy of FanDuel, here are the San Jose State-San Diego State odds:

College Basketball Odds: San Jose State-San Diego State Odds

San Jose State: +21 (-110)

San Diego State: -21 (-110)

Over: 126.5 (-110)

Under: 126.5 (-110)

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Why San Jose State Could Cover the Spread

The Spartans are getting 21 points, and they just won by 16. Moreover, San Diego State often struggles to score. San Jose State could lose 60-45 and cover the spread by six points.

Why San Diego State Could Cover the Spread

The Aztecs are in must-win mode. They're at home. San Jose State isn't likely to win two straight games. SDSU can easily get the jump on the Spartans and win a blowout.

Final San Jose State-San Diego State Prediction & Pick

San Diego State will win comfortably, but the Aztecs don't score regularly enough to merit a spread this large, against an opponent which is playing better, not worse, as the season nears its end. Aztecs 65, Spartans 48, feels like a good score.

Final San Jose State-San Diego State Pick: San Jose State +21