The Oklahoma Sooners (2-0) try to finish nonconference play undefeated when they host their longtime formal rival, the Nebraska Cornhuskers (2-1). It’s time to continue our college football odds series and make a Nebraska-Oklahoma prediction and pick based on Nebraska Oklahoma odds.

These two former Big Eight rivals are no stranger to each other. This will be their 87th matchup against one another. The Sooners control the historical record at 45-38-3 and won the most recent matchup 23-20 in the Big 12 Championship game in 2010.

Here’s how sportsbooks have set the Nebraska-Oklahoma Odds.

College Football Odds: Nebraska-Oklahoma Odds

Nebraska Cornhuskers +23 (-114)

Oklahoma Sooners -23 (-106)

Over 62 points (-110)

Under 62 points (-110)

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Why The Oklahoma Sooners Could Cover The Spread

The Sooners are 1-1 against the spread through their first two games. However, this will be their lowest spread line of the season as they were 31-point favorites in their first matchup against Tulane in Week 1 and were massive 52.5-point favorites against West Carolina last week. Note that when you make a Nebraska Oklahoma prediction.

Lincoln Riley looks to have another spectacular offense down in Norman this season. Oklahoma is currently second in the FBS in scoring offense averaging 58 points per game. Their Heisman favorite quarterback, Spencer Rattler, is off to a hot start completing 50 of his 65 passing attempting through the first two games and has six passing touchdowns to just two interceptions.

If you are to pinpoint one weakness for the Sooners offensively, it would be their run blocking. Oklahoma is currently averaging just 3.8 years per rushing attempt through their first two games.

What makes Oklahoma special this season is their improvement on the defensive side of the ball compared to previous seasons. According to Phil Steele's College Football 2021 Preview, the Sooners came into the year with the third-best defensively line in the country behind Clemson and Georgia. That hype is already looking to be true. Oklahoma has an 8.16% sack percentage and is allowing just 17 points per game.

Why The Nebraska Cornhuskers Could Cover The Spread

The Cornhuskers are 2-1 against the spread this season. However, Nebraska is just 2-6 ATS in their last eight games following a win. That's part of the Nebraska Oklahoma odds.

Nebraska earned their second straight win of the season, as they defeated Buffalo 28-3 at home in their last outing. It was their first back-to-back win since September of 2019. Scott Frost seems to have found the rhythm for this Cornhusker team — fast, fast, and more fast.  Against Buffalo, all four of Nebraska's touchdowns came from drives under two minutes. Keep that in mind when you make a Nebraska Oklahoma pick.

They go for the home run play, and it fits directly with their starting quarterback Adrian Martinez. His dual-threat capability forces defenses to stay honest. Martinez is 46 of 74 through for 728 years and his first three games and leads the team in rushing with 34 carries for 256 yards.

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Matthew Zemek ·

Matthew Zemek ·

Matthew Zemek ·

As exciting as the Cornhuskers offense can be if they go far this season, it will be due to their defense. Nebraska is holding opponents to 13.3 points per game and is allowing only 4.5 yards per play.

Final Nebraska-Oklahoma Prediction & Pick

The Oklahoma Sooners are a far superior team, but over three-touchdown favorites seem high. If Nebraska can avoid costly turnovers and slow down the passing attack of Spencer Rattler, they could turn this into a four-quarter game.

Also, this cannot be broken down quantitatively, but the emotional aspect of this game should be accounted for. Both fan bases will be rocking early with the nostalgia this old-time rivalry produces.

For those reasons, the Sooners will pull out a double-digit victory, but the Nebraska Cornhuskers will cover the spread.

FINAL NEBRASKA-OKLAHOMA PREDICTION & PICK: Nebraska Cornhuskers +23 (-114)