Andrew Luck and the Indianapolis Colts are heading into a key matchup with the Jacksonville Jaguars in Week 10 and are in need of another big win. After starting the season 1-5, the Colts have come back with two straight wins. Winning a third straight would make them an intriguing team to keep an eye on in the AFC South division race, even with the Houston Texans on a big run.

Indianapolis will have to deal with Jalen Ramsey this week and Luck had some praise to heap on him ahead of their matchup in a quote shared by Kevin Bowen of 1070 The Fan.

Indianapolis will have to be careful against a Jaguars' defense looking to prove a point. Jacksonville started the season looking like one of the teams to beat in the AFC, but have not played like it.

Jacksonville is 3-5 coming into the game with the Colts. Losing would put them in a tough position to come back and win the division. Part of their issues has been the offense, with Blake Bortles struggling mightily.

Ramsey will do everything in his power to stick with T.Y. Hilton this week. Andrew Luck and the Colts' offense will need to find ways to beat the Jaguars down the field.

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It will be interesting to see how this matchup turns out. Indianapolis has nothing to lose, while the Jaguars cannot afford to lose another game.

Frank Reich and the Colts will be coming out looking to be aggressive and it will be up to Ramsey and the defense to find ways to shut them down and give their team a chance to get a big win.