The Houston Texans and Indianapolis Colts are fighting for supremacy atop the AFC South. With these two teams just ahead of the Tennessee Titans and Jacksonville Jaguars, both of which remain in the mix for a divisional crown, the Texans and superstar quarterback Deshaun Watson will need to step up Thursday evening in Houston.

Because this upcoming Thursday Night Football matchup will surely play a very pivotal role for each team down the stretch, there is no doubt that Watson will come to play in Week 12. With a tough and prepared divisional rival coming to town in Houston, it will only amplify Watson's mindset as the Texans should be able to take care of business en route to regaining sole possession of the divisional lead heading into Week 13.

Deshaun Watson will throw for over 350 yards

After this past week's performance against the Baltimore Ravens, a game that saw the Houston Texans only score once, quarterback Deshaun Watson will surely come out with a vengeance on Thursday evening against the rival Indianapolis Colts. Not only did the Ravens rout the Texans with the team only scoring one touchdown, Watson did not even account for this score and threw an interception on top of that.

As a result, the Texans signal caller will be slinging the football all over the field this time around. Watson will throw for well over 350 yards against the Colts and might even eclipse the 400-yard passing mark to kickoff Week 12.

Deshaun Watson will rush for over 50 yards

Even though Houston Texans quarterback Deshaun Watson can sling the rock with the best of them, people often forget that the former Clemson Tigers standout can also use his legs. Watson is surely one of the best rushing quarterbacks in the entire NFL despite the fact that he is not lauded nearly enough for his ability to use his legs. However, that will change in Week 12 against the Indianapolis Colts.

While Watson will impress against a stout Colts defense with his arm, he will also do so by using his legs — and then some. Watson will rush for more than 50 yards on Thursday evening in Houston as the Texans offense will be rolling on all cylinders in each facet of the game.

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Deshaun Watson will score multiple rushing and passing touchdowns

If Houston Texans quarterback Deshaun Watson accounts for approximately 400 yards on Thursday Night Football against the Indianapolis Colts, the odds of him accounting for multiple touchdowns will be very likely. However, Watson will go above and beyond en route to rectifying last week's blowout loss at the hands of the surging Baltimore Ravens.

Watson will not only find the end zone by way of the passing and rushing games, but he will do so twice each. Watson will score two rushing touchdowns in addition to throwing for another pair of scores against the Colts as he attempts to take out his aggression from Week 11 on the divisional foe.