The Boston Red Sox and Houston Astros will continue the ALCS Friday night with the Astros taking a 3-2 series lead on Wednesday. It’s time to continue our MLB odds series and make a Red Sox-Astros prediction and pick.

The Red Sox and Astros will play Game 6 of the ALCS Friday evening, with the Astros having the ability to clinch a trip to the World Series with a win. Nathan Eovaldi will start for Boston and face Luis Garcia, who has struggled mightily for Houston this postseason. In two postseason starts, Garcia has allowed 10 runs in 3.2 innings. The Red Sox will hope that trend continues on Friday night as they look to force a Game 7 down three games to two.

Here’s how the bookmakers have set the Red Sox-Astros odds for Sunday’s game.

MLB Odds: Red Sox-Astros Odds

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Boston Red Sox -1.5 (+162), -106 ML

Houston Astros +1.5 (-196), -110 ML

Over 8.5 runs (-122)

Under 8.5 runs (-100)

Why the Red Sox can win this game

Garcia's struggles on the mound for Houston is a good start for Boston. They will hope to rattle him early like they did earlier in the series when he gave up five runs in one inning of work. The Red Sox have been an explosive offense at times this postseason, and they will look to get going as a group early in Game 6 with their season on the line. Having an edge in the pitching matchup is a solid start to Boston taking home the win and forcing Game 7. Enrique Hernandez and J.D. Martinez will look to power the Red Sox lineup in what is a must-win game for Boston.

Why the Astros can win this game

The Astros will be looking to clinch another trip to the World Series with a win on Friday. Their home crowd will be rocking, and starter Luis Garcia will look to get back on track after a pair of rough postseason starts. Garcia was 11-8 with a 3.48 ERA in the regular season, so his struggles in the postseason so far have been somewhat surprising. If Garcia can give the Astros some solid innings tonight, they'll be in a good position to take home the win and the AL Pennant.

Final Red Sox-Astros Prediction & Pick

With neither team throwing their respective ace, the over on the run total is a nice play tonight. Both teams have shown the ability to put up runs in the bunches throughout this postseason, so take the over and hope for a home run derby in Houston this evening. Take the two teams to combine for over 8.5 runs tonight in Houston.

FINAL RED SOX-ASTROS PREDICTION & PICK: Over 8.5 runs (-122)