The Denver Nuggets and Phoenix Suns will battle in a Western Conference, season opening matchup on Wednesday night. It's time to continue our NBA odds series and make a Nuggets-Suns prediction and pick.

The Nuggets and Suns will matchup for the season opener for the first time since the Suns demolished Denver in four games in the second round of the 2021 playoffs. Chris Paul is back with Phoenix, and they could be primed for another run. Nikola Jokic will look to defend his MVP trophy and get some revenge vs. the Suns in what is one of the better games on the Wednesday

Here's how the bookmakers have set the Nuggets-Suns odds for this Wednesday matchup.

NBA Odds: Nuggets-Suns Odds

Denver Nuggets +6  (-110), +194 ML

Phoenix Suns -6 (-110), -235 ML

Over 223 points (-110)

Under 223 points (-110)

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Why The Nuggets Can Cover The Spread

Anytime you have the league MVP, you have a shot. Jokic commands the floor like few big men ever have, running the Nuggets offense like a well oiled machine. While they are still missing Jamal Murray, they have plenty of other options to hold them over. Michael Porter Jr. will look to continue his role as the Nuggets second option, while the team as a group will have their hands full trying to guard a deep Suns group. Jokic putting up a huge game, with some punch added from Porter Jr. will probably be what it takes to beat a tough Suns group on their home floor come Wednesday night.

Why The Suns Can Cover The Spread

The Suns open the season on their home floor following their NBA Finals appearance earlier this year. They largely brought back the same group, and Paul and Booker will look to lead them on another quest for a high seed in the Western Conference. Deandre Ayton didn't get the new contract he wanted, so he may have extra motivation in the matchup vs. Jokic on Wednesday night. Coach Monty Williams will look to lead his Suns to a victory to kick off the new season. Denver's guards will likely have a tough time matching up with Paul and Booker, like they did in the playoffs.

Final Nuggets-Suns Prediction & Pick

The beginning of the season can be hard to predict in any sport, and the NBA is no different. Both of these teams have a lot of continuity from last season and should hit the ground running, but you just never know. The Suns should be hungry after coming up just short of a Larry O'Brien Trophy, but six points can be a lot in a game between two experienced playoff teams. Take the over rather than fading either of these two strong opponents.

FINAL NUGGETS-SUNS PREDICTION & PICK: Over 223 (-110)