Heading into Week 7 action against the San Francisco 49ers, the Los Angeles Rams have questions around the health of second-year wide receiver Cooper Kupp dealing with a sprained MCL.

According to Myles Simmons of TheRams.com, head coach Sean McVay on Wednesday afternoon officially ruled him out for Sunday's game.

This had come to be the expected designation especially since McVay had indicated earlier in the week that Kupp would “probably” miss the contest. Given the type of injury that he is dealing with the Rams are taking the precautionary approach with the entire situation.

Kupp has been a major part of their offense over his first two seasons in the league that has seen that taken up a notch this year as he has 30 catches for 438 receiving yards and five touchdowns. He is currently on pace to get notch 80 receptions for 1,168 receiving yards and 13 touchdowns. He has stood out as a huge asset both in the red zone and third down situations.

Although his absence will be felt on the field, the Rams have plenty of depth at the position led by two other highly productive receiving options in Brandin Cooks and Robert Woods. Among the two, Woods has been the more prominent factor in the passing game as he leads the team with 36 receptions for 524 receiving yards and three touchdowns Meanwhile, Cooks has shown to be a reliable all-around option fitting in as a deep-ball threat while showing he can be a possession threat.

The absence of Kupp could open up the opportunity for second-year wideout Josh Reynolds to get an increased role in the offense. Reynolds has recorded three catches on six targets for 37 receiving yards along with 10 rushing yards one attempt. The Rams also added a veteran wide receiver Nick Williams, who has previous experience with McVay dating back to his time with the Washington Redskins.