The Los Angeles Rams will be without a key figure in their NFC divisional round clash with the Packers on Saturday.

According to a report from Ian Rapoport of NFL Network,  Kupp has been ruled out of the team's matchup with Green Bay. While Kupp had been listed as a “game-time decision” following a knee injury that he sustained last week against the Seattle Seahawks, there was hope in the Rams organization that he would contribute against the top-seeded Packers.

Unfortunately for LA, those hopes won't be coming true.

Serving as a run-blocker late in their match against Seattle, Kupp subsequently fell to the ground clutching his knee in an injury that appeared to come despite little contact from the Seahawks defense. While he was eventually able to walk off the field, questions had remained about his ability to operate on the knee in the cold weather expected at Lambeau Field.

With the Rams already losing backup quarterback John Wolford and Jared Goff scheduled to play with pins in his thumb after recovering from surgery, the loss of Kupp could prove to be a fatal blow to an offense that has been inconsistent all season.

Without their top target available, wide receiver Robert Woods will take over the number one receiver spot. While Woods has been a deep threat all year for the Rams, he will have to operate in shorter routes to bail out the injured Goff. With the QB unable to deliver much power behind his throws thanks to the thumb injury, it will be imperative that the Rams provide him options in the middle of the field.

Upsetting a dominant Packers team at full-strength was likely to be a tall order for Los Angeles, now without their best receiver, that task becomes all the more difficult.