If the Toronto Raptors want to make it to the Eastern Conference Finals, they may have to do so without one of their best defensive players.

According to Adrian Wojnarowski of ESPN, Raptors forward OG Anunoby may miss the first two rounds of the playoffs as a result of acute appendicitis.

Anunoby underwent an emergency appendectomy on Thursday.

While Anunoby was a bit of a disappointment this season following a rather impressive rookie year, he was still a key member of Toronto's rotation all year long, playing in 67 games and averaging seven points and 2.9 rebounds over 20.2 minutes per game while shooting 45.3 percent from the floor, 33.2 percent from three-point range and 58.1 percent from the free-throw line.

Plus, the 21-year-old may be the Raptors' best wing defender not named Kawhi Leonard, so this could end up being a rather big loss.

Anunoby, who played his collegiate basketball at Indiana University, was originally selected by Toronto in the first round (23rd pick overall) of the 2017 NBA Draft.

He appeared in 74 contests and made 62 starts during his rookie campaign, registering 5.9 points and 2.5 boards across 20 minutes a night while making 47.1 percent of his field-goal attempts, 37.1 percent of his long-distance tries and 62.9 percent of his foul shots.

The London native caught the attention of many in last year's playoffs due to his impressive defense on LeBron James during the Raptors' second-round loss to the Cleveland Cavaliers.

Toronto won 58 games this season and captured the No. 2 seed in the Eastern Conference. It will open up its first-round playoff series at home against the Orlando Magic at 5 p.m. ET on Saturday.