UFC 263 is set for Saturday, June 12. It's one of the biggest fight cards of the year, as the main card is stacked with some of the top talent within the organization. The main event of the evening is a Middleweight title fight between Israel Adesanya and Marvin Vettori. It's time to continue our UFC odds series with an Israel Adesanya-Marvin Vettori prediction and pick.

Adesanya is coming off his first career loss after challenging the Light Heavyweight champion Jan Blachowicz for the belt. The Last Stylebender goes back to his natural weight class and looks to earn his fourth title defense in the Middleweight division.

Vettori is currently on a five-fight win streak and aims to become a champion for the first time in his career. His last loss was against Adesanya, which ended in a split decision. The Italian Dream plans to create a different ending in the highly anticipated rematch.

Let's take a look at the dds sportsbooks have set for the main event.

UFC 263: Israel Adesanya-Marvin Vettori odds

Israel Adesanya -265

Marvin Vettori +225

Over 4.5 rounds (-135)

Under 4.5 rounds (+105)

How Israel Adesanya wins the fight

The current Middleweight champion is an elite kickboxer who uses his height and reach to his advantage. At 6-foot-4, Adesanya will be looking to keep his distance and make clean, accurate strikes. He'll be working as a sniper, keeping Vettori at bay throughout the fight. Adesanya also utilizes a unique fighting style, as he consistently switches his stance to keep his opponents guessing. We should be seeing The Last Stylebender at peak performance on Saturday night.

Although he is much taller than Vettori, maintaining distance is much easier said than done. His opponent likes to take it to the mat, which means Adesanya will need to have perfect takedown defense in this one to keep his belt. The last fight was an all-out war, and Israel Adesanya will be prepared for another one in his upcoming matchup.

How Marvin Vettori wins the fight

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Marvin Vettori's game plan will be the exact opposite of Adesanya's strategy. The Italian Dream is a known wrestler and Jiu-Jitsu artist. In fact, nine of his 17 career wins have come via submission. We witnessed Vettori's elite grappling skills in his last bout against Kevin Holland, where Vettori controlled the cage with constant takedowns.

Look for Vettori to attempt a similar game plan. Adesanya is one of the best in the world at defending takedowns, so the Italian will have to be patient and take his time. A solid game plan would be to work the clinch and get inside of Adesanya's guard, work the body, then take Adesanya down once he's tired.

Final Israel Adesanya-Marvin Vettori prediction & pick

Similar to their first fight, this one should be close throughout. Adesanya is the favorite to win the bout, as he has dominated the Middleweight Division entirely. However, Vettori has come the closest to defeating The Last Stylebender, which bodes well for Vettori's confidence. Due to the style of these fighters, it likely goes the distance, which is why it's favored to go over 4.5 rounds. This one should go the distance, and could be a toss-up that comes down to the judges.

FINAL PREDICTION AND PICK: Marvin Vettori wins by Split Decision