The Chicago White Sox have been downright dreadful this season and are coming into this road matchup against the Tampa Bay Rays in hopes of getting some momentum back on their side when they continue their road trip at Tropicana Field in this Wednesday night matchup. It is time to continue our MLB odds series with a White Sox-Rays prediction, pick, and how-to-watch.

The Chicago White Sox continue on their road trip Wednesday evening for a clash with the Tampa Bay Rays. The White Sox look to bounce back after a tough loss, with Chris Flexen on the mound seeking to contain the Rays' patient offense. The Rays, always a threat at home, counter with Aaron Civale. Expect a classic pitcher's duel with both teams relying on their pitching staff to shut down the other's bats as the White Sox look to get some momentum before leaving Tampa Bay in this Wednesday night matchup.

The Trop gets electric Wednesday night as the Tampa Bay Rays face the visiting Chicago White Sox! The Rays, boasting a stingy pitching staff led by Aaron Civale, aim to shut down the White Sox' bats and extend their home winning streak. Chris Flexen counters for Chicago. The Tampa Bay Rays will be looking to continue their hot streak at the plate and on the mound when they welcome the White Sox to Tropicana Field for game three of this series in this Wednesday night matchup.

Here are the MLB Odds, courtesy of FanDuel. 

MLB Odds: White Sox-Rays Odds

Chicago White Sox: +1.5 (-111)

Moneyline: +190

Tampa Bay Rays: -1.5 (-108)

Moneyline: -230

Over: 8.5 runs (+100)

Under: 8.5 runs (-122)

How to Watch White Sox vs. Rays

Time: 6:50 PM ET/3:50 PM PT

TV: Bally Sports Sun, NBC Sports Chicago, MLB Extra Innings

Stream: fuboTV (Click for free trial)

Why The White Sox Will Cover The Spread/Win

Wednesday night's matchup at Tropicana Field pits the Chicago White Sox, hungry for a win, against the Tampa Bay Rays and their rising star Aaron Civale. While the Rays are a force to be reckoned with at home, the White Sox, with Chris Flexen on the mound, have the potential to pull off an upset on the road.

Flexen, a blossoming right-hander, has quietly been a dependable arm for the White Sox this season. He throws a mix of pitches that keeps hitters guessing, featuring a deceptive changeup that complements his fastball nicely. His ability to locate effectively and limit walks has resulted in a solid 4-3 record and a 3.62 ERA. More importantly, he thrives under pressure, pitching with poise in key situations.

On the other hand, Civale, despite showcasing flashes of brilliance, can be streaky at times. While his fastball has good zip and his curveball can buckle knees, he's prone to command issues that can inflate his pitch count. The White Sox' lineup, boasting veterans like Jose Abreu and Tim Anderson, can capitalize on any mistakes Civale makes and force him out of the game early.

The White Sox' offense seems to be waking up after a sluggish start. Their aggressive approach at the plate, coupled with Flexen's ability to keep the Rays in check, could create an opportunity for Chicago to steal a victory on the road. The key for the White Sox lies in putting together quality at-bats against Civale and capitalizing on any scoring opportunities early.

This matchup presents a fascinating contrast: a surging Flexen looking to solidify his role in the White Sox rotation, facing a talented but sometimes inconsistent Civale. While the Tropicana Field environment can favor the Rays, the White Sox's offensive potential and Flexen's recent form give them a fighting chance. If they can jump on Civale early and limit baserunners, Chicago can silence the Rays' crowd and secure a much-needed win.

Why The Rays Will Cover The Spread/Win

The Tampa Bay Rays return to the friendly confines of Tropicana Field on Wednesday night, looking to overpower the visiting Chicago White Sox with Aaron Civale on the mound. While Chris Flexen has been a pleasant surprise for the White Sox, the combination of Civale's talent and the Rays' aggressive offense positions Tampa Bay for a victory on their home turf.

Civale, a young righty with a bright future, possesses a diverse arsenal that can baffle hitters. His fastball features good movement, and his curveball has the potential to drop hitters to their knees. While he can be prone to walks at times, Civale thrives at home, where the Trop's unique dimensions can work to his advantage. Look for him to use his pinpoint control to exploit the White Sox' tendency to strike out.

On the other side, Chris Flexen, despite his recent improvement, presents a more exploitable matchup for the Rays' potent offense. His fastball lacks overpowering velocity, and his off-speed pitches haven't always been as sharp. The Rays' hitters, led by the ever-dangerous Randy Arozarena and the patient Brandon Lowe, can take advantage of any mistakes Flexen makes and force him to work hard early in the count.

Furthermore, the Tropicana Field can be a graveyard for opposing hitters. The quirky dimensions and the “roof effect” can suppress home runs and create a haven for pitchers like Civale who rely on control and deception. The Rays, accustomed to their home environment, should feel comfortable at the plate while Flexen might struggle to adjust.

The Rays' bullpen, boasting the shutdown arm of Diego Castillo, is well-rested and ready to protect a lead late in the game. This experience edge could prove crucial against a White Sox team that sometimes struggles to manufacture runs in the later innings, especially in unfamiliar territory.

While Flexen has been a bright spot for the White Sox, facing a talented Civale and a hungry Rays lineup at home presents a significant challenge. The combination of Civale's well-rounded pitching, the Rays' offensive firepower, and the Tropicana Field advantage makes Tampa Bay the favorite on Wednesday night. Look for the Rays to capitalize on their home-field edge and Flexen's vulnerabilities to secure a convincing victory.

Final White Sox-Rays Prediction & Pick

This should be an exciting matchup between two teams full of young talent. The Atlanta Braves boast one of the more potent lineups in the majors and is going to give up-and-coming hurler Ketter Crawford a ton of problems, especially in hitter-friendly Truist Park. It's up to Reynaldo Lopez to limit the damage on his side and if he can do so expect the Braves to pounce on Crawford and get a much-needed home victory to cut into the Phillies lead atop of the NL East.

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Final White Sox-Rays Prediction & Pick: Tampa Bay Rays -1.5 (-108), Under 8.5 runs (-122)