The New York Giants and New Orleans Saints will battle in an NFC matchup on Sunday. It's time to continue our NFL odds series and make a Giants-Saints prediction and pick based on Giants Saints odds.

The Saints will look to go to 3-1 on the season while the Giants will continue to look for their first win after another narrow loss last Sunday at the hands of the Atlanta Falcons.

Here's how the bookmakers have set the Giants-Saints odds for this Sunday matchup.

NFL Odds: Giants-Saints Odds

New York Giants -7.5 (-115)

New Orleans Saints +7.5 (-105)

Over 41.5 points (-115)

Under 41.5 points (-105)

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Why The Giants Can Cover The Spread

James Winston. If the Saints had a better quarterback, this line would be higher. New Orleans has a very solid offensive line and a great defense. Sean Payton remains one of the best coaches in the league, and he has a deep and talented roster to toy with. Also, Winston has averaged just 129 passing yards per game this season, as Payton has leaned on Alvin Kamara and the running game in an effort to limit the turnovers Winston has been notorious for committing throughout his career. Consider this when making your Giants Saints prediction.

The recipe to a cover for the Giants is to get Winston to turn the ball over. It could be tough sledding for Daniel Jones and Saquon Barkley against the Saints defense, so they'll need the benefit of good field position or maybe even a defensive score from their defense if they are going to win this game. To cover, they need Jones to limit turnovers in his own right, while limiting the New Orleans rushing attack and forcing Winston to make plays.

Why The Saints Can Cover The Spread

New Orleans is the better team across the board, as evidenced by the 7.5-point line. Despite not having particularly great quarterback play, the Saints have found ways to move the ball this season. Kamara also remains one of the best backs in football, and their defense makes plays to set them up with good field position. Winston has done a decent job of managing the game for the Saints this season, and against an 0-3 Giants team, he may not need to do any more than that again on Sunday. This explains the Giants Saints odds.

The Saints defense should cause problems for Jones and the New York offense, as Jones as been a turnover-plagued quarterback as well throughout the early stages of his NFL career. New Orleans is sixth in yards per game allowed defensively and third in points allowed. The Saints will also be playing in the Caesars Superdome for the first time this season as they were forced to play in Jacksonville to open the season due to Hurricane Ida. The crowd will be as intimidating as ever come Sunday afternoon you would think. Include this thought in your Giants Saints pick.

Final Giants-Saints Prediction & Pick

The Saints returning to a Superdome full of fans is hard to bet against. Their defense has led the way for them this season and that could again be a recipe against a struggling Giants team. This is what observers and football students have to think about when they sit down and make their Giants Saints pick.

FINAL GIANTS-SAINTS PREDICTION & PICK: Saints -7.5 (-105)