After a disappointing exit in the Wild Card Round of last year's playoffs, the Pittsburgh Steelers will be back with a vengeance in 2021 and looking to do some serious damage in the hopes of making one last Super Bowl run before Ben Roethlisberger decides to hang up his cleats.

Hoping for a better outcome than last season, the Steelers have done a lot of work this offseason to improve their roster.

Drafting Najee Harris will definitely bolster their running game, and the acquisition of Ahkello Witherspoon will give them additional depth in their secondary. With Mike Tomlin looking to make serious adjustments to give them a new and improved game plan, the Steelers will be flying under the radar as an overlooked title contender heading into next season.

This is especially true with two-time Super Bowl champion and All-Pro quarterback Ben Roethlisberger still under center for them and a strong receiving corps in place for the 2021 NFL season. Let us now discuss four bold predictions for the Steelers' Week 1 matchup against the Buffalo Bills, another Super Bowl hopeful.

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Steelers Week 1 predictions

Najee Harris will put up big numbers in NFL debut with Steelers

Coming off a highly productive tenure at Alabama, Najee Harris will look to make his mark in the NFL during the Steelers' Week 1 matchup against the Bills. Looking to help the Steelers improve their running game and provide Roethlisberger with a ton of help in the backfield, Harris has the potential to put up big numbers in his pro debut with Pittsburgh. At 6-foot-2 and 230 pounds, Harris has a potent combination of speed and power to go along with a well-rounded game that allows him to excel in many facets of the game.

With a ton of upside and a wide array of skill sets at his disposal, the Bills will have a tough time tackling Harris all game long. Whether he's coming out of the backfield or catching a slant pass, Harris will prove to be a matchup nightmare for the Bills' defense on Sunday. So, look out for Najee Harris to make some big plays and elevate the Steelers' running game in Week 1.

Ben Roethlisberger will post big numbers

After a poor showing in the Steelers' Wild Card matchup against the Cleveland Browns, Ben Roethlisberger is back with a chip on his shoulder and hopes to be firing on all cylinders right out of the gate. With a top-notch receiving corps and promising rookie running back Najee Harris in the fold for them, Roethlisberger can be expected to put up some big numbers on Sunday against the Bills.

With his quarterback vision, accuracy, and deep arm threat, Roethlisberger will be looking like the same quarterback who previously led this team to two Super Bowl titles. Looking to get this team back into the elite of the AFC in 2021, Ben Roethlisberger will be playing lights out this Sunday.

T.J. Watt and Minkah Fitzpatrick disrupt the Bills' offense

With a star-studded defensive unit at the helm for the Steelers and an elite offense coming their way on Sunday, T.J. Watt and Minkah Fitzpatrick will have their hands full. Looking to shut down down their receiving corps and lock down their running game, the Steelers' defense will be alert and ready to lock up the Bills' explosive offense at all costs.

Come Sunday afternoon, watch out for this Steelers squad to disrupt the flow of the Bills' offense and make a killing off their shortcomings. Looking to rebound from a tough postseason outing in 2021, the Steelers are bound to make things difficult for the Bills and completely take them out of their element.

The Steelers will come away with a surprise win in Week 1 

Ready to turn things around and get back to title contention in 2021, this hungry and determined Pittsburgh Steelers squad will be bringing the fight against this powerful Bills team all day long. With seasoned champions in Roethlisberger and Mike Tomlin leading the charge, this resilient and reliable Steelers team definitely has the talent and grit to overcome this AFC juggernaut and start off their 2021 campaign on a high note.

After enduring a serious blow during last year's playoff run, the Steelers will look to prove all the naysayers wrong and come out stronger than ever to start off their season. Now that Ben Roethlisberger is nearing the end of his career and looking for one last Super Bowl run, getting a win on Sunday could be the start toward something special in 2021. This game against the Bills will be a tough matchup for the Steelers, but it will be a winnable one for them as well.