UFC 266 should be a great card as it kicks off with Jessica Andrade versus Cynthia Calvillo. Everything is on the line in this Women's Flyweight bout, as the winner is sure to receive a title shot. It's time to continue our UFC odds series with a Jessica Andrade-Cynthia Calvillo prediction and pick.

Andrade is currently ranked as the number one contender in the Women's Flyweight division. It's been a rough go for her recently as she's gone 2-3 in her last five fights, albeit, Andrade has faced the best the division has to offer.

Calvillo is coming off of a tough loss from Katlyn Chookagian. Even so, she's still ranked in the top five of her division and a win over Andrade should catapult her to a potential title shot.

Here's how the sportsbooks have set the odds for this UFC 266 Women's Flyweight bout.

UFC 266 odds: Jessica Andrade-Cynthia Calvillo odds

Jessica Andrade (-235)

Cynthia Calvillo (+200)

Over 2.5 rounds (-165)

Under 2.5 rounds (+135)

How Jessica Andrade wins the fight

“Bate Estaca” is well known as a striker. Although she gives up the height and reach advantage in nearly every fight, Andrade utilizes smooth boxing skills in her matchups. Her head movement is elite and she's able to keep her opponents guessing. Andrade also does a fantastic job attacking the body and the head, offering a well-balanced level change her opponents struggle to defend.

This is a dangerous fight for Jessica Andrade at UFC 266. Andrade is used to being shorter than her opponents, which allows her to work inside. However, Cynthia Calvillo is a grappler who will be looking for the clinch. Andrade will have to utilize her speed to evade takedowns, as her best bet is to keep it on the feet. Look for Andrade to throw quick combinations and use her footwork to avoid the clinch.

How Cynthia Calvillo wins the fight

Five of her nine career wins have been finishes. Cynthia Calvillo is a tough fighter who tends to control her matches on the ground. This is going to be her strategy at UFC 266, as her skills on the mat give her a nice advantage over her opponent. If she can do that, we should be seeing Calvillo's hand raised at the end of the bout.

Taking Jessica Andrade down is a tough goal to accomplish. Her size allows her to defend takedowns at a high rate. To earn the win at UFC 266, Cynthia Calvillo will need to work the clinch, press her opponent against the cage, and take Andrade down from there. Look for Calvillo to try and control the octagon, as that'll give her the best route to victory.

Jessica Andrade-Cynthia Calvillo prediction & pick

This fight should be electric. It's a classic striker versus grappler matchup and has the makings to set the tone for UFC 266. Jessica Andrade is the favorite to win this fight. However, her size disadvantage forces her to close the distance with her opponent. This works directly into Calvillo's wheelhouse, as this increases the opportunity to get the clinch and achieve the takedown. This one could go the distance, but we could see a big upset on Saturday night.

FINAL JESSICA ANDRADE-CYNTHIA CALVILLO PICK: Cynthia Calvillo wins via Unanimous Decision