The Cardinals have been plagued with devastating injuries recently in crucial parts of their game. Unfortunately, the huge void of playing without DeAndre Hopkins will not be filled for Week 11. NFL reporter Ian Rapoport tweeted that the wide receiver has been ruled out for Sunday.

Hopkins hasn't made an appearance on a game-day field the entire month of November. His last game was in their first loss of the season against Green Bay back on October 28th. Even before this game, Hopkins was dealing with the same hamstring injury that has him sidelined this week. He was on the Cardinals injury report as a non-participant in practice prior to their Week 8 loss.

As stated previously, Hopkins will not make an appearance for Sunday's matchup against the Seahawks. which is a huge loss for the Cardinals offense. He already has 7 touchdowns this season, along with 35 receptions and 486 receiving yards.

The Cardinals are also at a loss in their quarterback position. Like Hopkins, promising quarterback Kyler Murray has been inactive since the late October game. He left the field and did not return after suffering an ankle sprain. This sprain has forced him to sit out their last two games: a win against the 49ers and a loss against the Panthers. However, Murray is a game-time decision for the Cardinals. If he is healthy, Murray is expected to be the starting quarterback.