The Minnesota Vikings will face off with the Los Angeles Chargers in what should be one of the most exciting matchups of Week 10. It's time to continue our NFL odds series and make a Vikings-Chargers prediction and pick.

The Vikings are one of the many teams that have fallen short of expectations this season. Most thought that head coach Mike Zimmer's squad would be playing in a wild card game at the very least, but if they keep playing like they have been the Vikings will watching the wild card from the couch. A matchup with quarterback Justin Herbert and the Chargers could help turn things around. Los Angeles has had a rough couple of weeks, as losses to the Baltimore Ravens and New England Patriots exposed some weaknesses. A narrow win against the Philadelphia Eagles didn't do much to inspire confidence, so it will be telling to see how the Chargers approach this matchup.

Here's how the bookmakers have set the odds for the Vikings-Chargers game.

NFL Odds: Vikings-Chargers Odds

Minnesota Vikings: +3 (-106)

Los Angeles Chargers: -3 (-114)

Over: 53.5 (-105)

Under: 53.5 (-115)

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Why the Vikings Could Cover The Spread

At first glance, this is a bad matchup for Minnesota. The Chargers have the third-best pass defense in the NFL, as they allow only 197 passing yards per game. However, there's reason to believe that the Vikings will fare well throwing the ball here. Los Angeles will likely be missing two starting defensive backs, as neither Michael Davis or Nasir Adderley have practiced this week. Those are two key defenders for Los Angeles, and it takes a full team to stop the combination of Adam Thielen and Justin Jefferson. Expect the Vikings to boast a solid passing attack here.

While the Chargers' pass defense has been one of the league's best, the same can't be said about their run defense. It feels like this is a perennial problem with Los Angeles, and this is season is no different. Head coach Brandon Staley's team allows a whopping 163 rushing yards per game, good for dead last in the NFL. The Chargers also allow opposing running backs to average an incredible five yards per carry. Minnesota is one of the best rushing teams in the league, so this is a dream matchup for the Vikings.

Why the Chargers Could Cover The Spread

Both offenses have a pretty solid matchup in this game. Quarterback Justin Herbert should have an easy time against this Vikings defense that has been just below league average against the pass. There's a chance that this pass defense is shorthanded, as cornerbacks Cameron Dantzler and Bashaud Breeland have both been listed on the Week 10 injury report. Linebacker Anthony Barr, a key part of everything that Minnesota does on defense, hasn't practiced at all. This is the same defense that looked totally incapable of stopping backup quarterback Cooper Rush, so it's tough to envision them faring well against one of the best passing offenses in the NFL.

Los Angeles doesn't usually have a big home field advantage, but playing in SoFi Stadium will certainly benefit the Chargers here. Herbert has played better at home this season, throwing for more yards, more touchdowns, and more yards per game on average. The visiting Vikings are also 1-3 on the road this season, and this is their second week in a row playing away from home. Los Angeles should be able to capitalize on their home turf here.

Final Vikings-Chargers Prediction & Pick

Taking the Chargers is certainly tempting, but it isn't the bets pick here. Minnesota has been in several similar situations this season, and the game has come down to the wire every time. Instead, the over is the best pick on the board.

Final Vikings-Chargers Prediction & Pick: Over: 53.5 (-105)