The Green Bay Packers will head into Week 3 with some potentially game-changing players forced to watch from the sidelines.

According to Packers head coach Mike McCarthy, veteran wideout Randall Cobb and defensive end Mike Daniels are considered doubtful for this week’s matchup against the Cincinnati Bengals, via ESPN’s Rob Demovsky.

The doubtful list reads like a who’s who of key players: wide receiver Randall Cobb (chest), left tackle David Bakhtiari (hamstring), defensive tackle Mike Daniels (hip), cornerback Davon House (quad), outside linebacker Nick Perry(hand), linebacker Jake Ryan (hamstring, concussion) and top backup safety Kentrell Brice (groin).

Along with Cobb and Daniels, Jordy Nelson and Bryan Bulaga are currently considered questionable for Week 3, via Demovsky.

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Two more, receiver Jordy Nelson (quadriceps) and right tackle Bryan Bulaga (ankle), were questionable.

After a season-opening win over the Seattle Seahawks, the Packers once again fell short against the Atlanta Falcons on the road in Week 2. It may be difficult for Aaron Rodgers and company to get back on track without some of these weapons on both sides of the football on Sunday, but Cincinnati has struggled this season and may be a team in which Green Bay can pull out a win even without some of their best players.

As for the rest of the season, the Packers will hope to get their core players healthy with a potentially crucial matchup with the Dallas Cowboys on the horizon in Week 5.