The San Francisco 49ers playoff matchup against the Los Angeles Rams should be a great contest. The winner will determine the representative of the NFC in the Super Bowl. Both franchises will be giving it their all. We take a look at this 49ers-Rams game with some of our 49ers playoff predictions in mind.

It'll be a tough matchup, but the 49ers have the tools to compete with anybody. The Rams have a sturdy defense, so San Francisco will need to step it up on offense. For that reason, we should expect big performances out of George Kittle, Deebo Samuel, and Jimmy Garoppolo.

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If everything comes together, the 49ers can win on Sunday. They have one of the best defenses in the league, particularly in the front seven. Look for San Francisco to attack Matthew Stafford all day as they hope to knock him off-kilter. If that comes to fruition, we might be witnessing an upset in the championship round of the 2022 NFL playoffs.

With that said, here are four bold 49ers' playoff predictions for their upcoming matchup against the Rams.

Here are the Cardinals-Rams NFL odds, courtesy of FanDuel. 

49ers Playoff Predictions

4. George Kittle leads his team in receiving yards

George Kittle has been a bit inconsistent in the passing game this year, but he's still one of the best tight ends in the league. What he does as a blocker is elite and the 49ers will need that on Sunday. However, what's more crucial, is Kittle's ability as a receiving threat.

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For the 49ers to defeat the Rams, George Kittle needs to be involved in the game plan. He's tough to bring down, making him tremendous after the catch. San Francisco should highly consider utilizing their superstar tight end, as he provides them with a legitimate advantage against LA.

3. Deebo Samuel goes bonkers for 125+ total yards and 1 touchdown

Otherwise known as the human Swiss Army Knife, Deebo Samuel is bound to be heavily involved in the 49ers game plan. He's dangerous as a receiver and has proven to be reliable in the run game. For that reason, San Francisco will do everything they can to feed Samuel the ball all day.

2. Jimmy Garoppolo makes a case to be the starter next year

People give Jimmy Garoppolo a ton of flack, but the truth of the matter is he finds a way to win in the postseason. Sure, he's surrounded by legit talent, but he's come through when it matters most for his team. Even so, Garoppolo needs to be at his best against the Rams, as Los Angeles has one of the most dangerous defenses in the NFL.

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This will be a tough game for the 49ers and Garoppolo. The Rams won't take them lightly, as San Francisco has had their number recently. Regardless, Jimmy Garoppolo will have a chance to prove to the world he deserves to be the starting quarterback right now, and for the future of this franchise. Despite how many fans are ready for Trey Lance, Garoppolo continues to prove the doubters wrong.

1. 49ers find a way to win and go to Super Bowl 56

Many aren't giving San Francisco a chance but there are reasons to believe they can pull off the upset. For starters, the 49ers have dominated the Rams recently, as Kyle Shanahan has out-coached Sean McVay so far. Furthermore, this team matches up well with LA in general. This one should come down to the wire and Kyle Shanahan will give his team a chance to win on Sunday.