The Baltimore Orioles hit the road for the first time this season to take on the Pittsburgh Pirates Friday night. Below we will continue our MLB odds series with a Orioles-Pirates prediction and pick. We will also let you know how to watch the game.

The Orioles have started the season 4-2 by taking two of three games from the Los Angeles Angels and Kansas City Royals. Baltimore's batting average as a team is not great, but they have scored 36 runs in six games. Adley Rutschman is batting .333 while Ryan Mountcastle is right at .300. On the mound, the Orioles have been able to throw really well. They have a 3.33 ERA and 1.00 WHIP, so their pitching has been a big bright spot.

The Pirates have started the season 6-1, so they are playing better than anybody would have thought. Pittsburgh is one of the better offensive teams, but those seven games were against the Miami Marlins and Washington Nationals. Pittsburgh has also been pretty solid on the mound. They have a 3.82 ERA and 1.20 WHIP.

Grayson Rodriguez will get the ball for the Orioles. Jared Jones will start for the Pirates.

Here are the MLB Odds, courtesy of FanDuel. 

MLB Odds: Orioles-Pirates Odds

Baltimore Orioles: -1.5 (+126)

Moneyline: -136

Pittsburgh Pirates: +1.5 (-152)

Moneyline: +116

Over: 8 (-110)

Under: 8 (-110)

How to Watch Orioles vs. Pirates

Time: 4:12 PM ET/1:12 PM PT

TV: SportsNet Pittsburgh, MASN

Stream: fuboTV (Click for free trial)

Why The Orioles Will Cover The Spread/Win

Grayson Rodriguez ended the 2023 season as one of the better pitchers in the MLB. He began 2024 right where he left off. In his first start of  the season, Rodriguez gave up one run on four hits through six innings of work. He also struck out nine batters and walked just one in the win over the Los Angeles Angeles. He is locked in right now, and that will not change in Pittsburgh. If he can continue to pitch well, the Orioles are going to win this game on the road.

Why The Pirates Will Cover The Spread/Win

The Pirates have Jared Jones on the mound, and he pitched very well in his first start. Against the Marlins, Jones threw 5.2 innings, allowed three runs on three hits, but he struck out 10. The three runs could be a tad better, but the Pirates got the win, and he was pretty much dominant. The Orioles offense has not been great to begin this season, so Jones has a good chance to continue his hot start.

The Pirates have been very good with their bats this season. They are batting .283, with 49 runs scored. That is seven runs a game and they are averaging over 10 hits per game. The Pirates have a very tough matchup Friday afternoon, but their bats are all tough outs. If they can continue to be good at the plate, the Pirates will win their home opener.

Final Orioles-Pirates Prediction & Pick

This is going to be a good game between two good pitchers. In my opinion, Rodriguez has really proven himself and shown he is here to stay. Jones is a good pitcher, but I like Rodriguez and the Orioles offense a little better in this matchup. For this reason, I am going to take the Orioles to win this game straight up.

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Final Orioles-Pirates Prediction & Pick: Orioles ML (-136)