The main event of the evening for UFC 260 is one of the most highly anticipated heavyweight matchups in MMA history. Stipe Miocic has fought in seven straight title bouts and will be fighting in his eighth on Saturday night. Miocic considered to be one of the best heavyweight fighters in UFC history and aims to defend his belt against Francis Ngannou. “The Predator,” otherwise known as Francis Ngannou, is considered to be one of the best knockout artists of all time. With a four-fight win streak all ending by knockout, Ngannou aims to claim the heavyweight throne for the first time in his career. Making a Miocic vs Francis prediction isn't going to be easy, but someone's got to win in this match.

Miocic is a fan favorite, especially in the state of Ohio. He's a part-time firefighter while also being the UFC Heavyweight champion of the world. This is the second time he'll be facing Ngannou in the Octagon and aims to repeat that performance with a victory.

In three of the last four fights, Ngannou has ended the fight by knockout in under one minute. That fourth fight? Only took one minute and eleven seconds. He's ending fights with ease, which makes him one of the most dangerous fighters in the UFC right now. This is his first title fight since he last fought Stipe Miocic back in 2018, however, he has a legitimate chance to walk away with the belt this time.

Let's take a look at the opening odds the sportsbooks have on the main event of UFC 260.

UFC 260: Stipe Miocic – Francis Ngannou Odds

Francis Ngannou's net worth in 2021, UFC 260, Francis Ngannou

Stipe Miocic (+120)

Francis Ngannou (-140)

Over 1.5 rounds (-150)

Under 1.5 rounds (+120)

How Stipe Miocic Wins the Fight

Highly considered as one of the best heavyweight fighters in UFC history, Miocic looks to further prove his dominance by securing a win over Francis Ngannou. He enters this title bout as the slight underdog, but his prowess in the Octagon gives him a great shot at retaining his title. With so much on the line, look for Stipe to follow through with a solid game plan to secure a victory.

Even though Francis Ngannou is so dangerous on his feet, Miocic is too. His best bet in winning this title bout is to keep it on the feet and kickbox his way to victory. A dangerous game plan, but sticking to his strengths will be how Miocic walks away victorious from this one. Any punch can end this fight at any moment. Don't blink because a strong hook from Miocic could be enough to end the fight early.

How Francis Ngannou Wins the Fight

Ngannou has made his last four fights look easy after winning each one via knockout, the longest one only being one minute and 11 seconds. The Predator looks to earn the heavyweight belt for the first time in his career while also revenging his loss to Stipe back in 2018. Miocic isn't known to take it to the ground, which is perfect for Ngannou in this matchup.

Look for this fight to remain standing throughout, as both fighters will likely stand and bang. It might go to the clinch against the cage a few times, but for the most part, both fighters will keep their distance and throw heavy haymakers whenever they get the chance. This fight leans in Ngannou's favor as he's been so dangerous recently. To walk away with the belt, it's likely Ngannou needs to end the fight early. If it goes the distance, that likely means the fight went in Miocic's favor. Look for Ngannou to come out swinging as he'll want to end this fight as soon as possible.

UFC 260 ODDS Stipe Miocic-Francis Ngannou PREDICTION: Francis Ngannou wins by Knockout in the first round