The Chuck Pagano era has officially come to an end with the Indianapolis Colts after six seasons, the team announced on Sunday. Pagano was fired by the team after the Indianapolis finished their 2017-18 campaign with a 4-12 record.

Owner and CEO Jim Irsay made a statement about Pagano after Indy's 22-13 victory during Week 17 over the Houston Texans.

“Chuck Pagano provided Colts fans with many exciting wins and memories as head coach of the Colts,” Irsay said. “Throughout his tenure in Indianapolis, he impacted the lives of the players he coached, those who he worked with in the organization and Colts fans across the globe. Chuck’s first season was one of the more inspirational stories in NFL history as he courageously battled and overcame leukemia. As a result, his CHUCKSTRONG Foundation has raised millions for cancer research. We are thankful for Chuck’s contributions to our franchise and community and we wish him, Tina and the entire Pagano family nothing but the best moving forward.”

Over his six seasons as head coach in Indianapolis during the regular season and postseason, Pagano compiled a 56-46 career record at the helm. This also included three straight 11-5 regular season finishes from 2012-14.

During the 2012-13 NFL season, Pagano missed 12 games due to his battle with leukemia but rallied the Colts to the playoffs. Pagano founded The CHUCKSTRONG Foundation, which has raised over $4.7 million for cancer research over a five-year period.