Indianapolis Colts quarterback Andrew Luck is dealing with a couple of injuries, and his status for Week 1 of the regular season is very much up in the air. However, the Colts have “guarded optimism” that Luck will be able to play in the season opener, according to Chris Mortensen of ESPN.

Luck was initially thought to just be dealing with a calf issue, but earlier this week, Colts owner Jim Irsay stated that Luck also had an injury with a “small little bone.” It was later revealed that it was an ankle sprain.

The 29-year-old began experiencing calf problems back in April, and the issue resurfaced this summer, causing Luck to sit most of training camp thus far. He is also not expected to play in the preseason at all.

This marks the second time in three years that Luck's regular season has been in jeopardy. Remember: back in 2017, Luck was coming off of shoulder surgery and was expected to be ready sometime early in the season, but he had multiple setbacks and ended up missing the entire 2017 campaign.

Obviously, his current injury issues don't seem nearly as problematic, but the situation likely does not conjure up good memories in Indianapolis.

The Colts are considered by many to be Super Bowl contenders heading into 2019, but if Luck is at all compromised, those hopes completely go out the window.

Luck is coming off of a 2018 campaign in which he threw for 4,593 yards, 39 touchdowns, and 15 interceptions while completing 67.3 percent of his passes and posting a passer rating of 98.7.