The Toronto Raptors will be without the services of Kyle Lowry and Serge Ibaka for Wednesday night's home game against the Indiana Pacers, according to a report from Blake Murphy of The Athletic.

For Lowry, this marks the second straight game he'll be sidelined due to a thigh contusion. Needless to say, it's a tough blow for the Raptors.

In 29 appearances with the Raptors this season, Lowry has racked up averages of 14.2 points on 43.6 percent shooting from the field (33.0 percent from beyond the arc), 10.0 assists, 4.4 rebounds, and 1.4 steals in 34.2 minutes per outing.

With Lowry ruled out, the Raptors will likely call on Fred VanVleet, who has been upgraded to probable after missing one game due to a back issue.

As Murphy reports, Ibaka will also be unavailable for Wednesday night's game, which leaves the Raptors rather short-handed in the front-court. Jonas Valanciunas, who's dealing with a thumb injury, is also unavailable for Wednesday's game. That means Greg Monroe and Pascal Siakam will likely see an uptick in their usage rates.

Ibaka has played in 31 games with Toronto this season, averaging 16.7 points on 55.2 percent shooting from the field (28.8 percent from downtown), 7.5 rebounds, 1.3 assists and 1.4 blocks in 27.9 minutes per contest.

Wednesday night's Raptors-Pacers game is scheduled to tip inside Scotiabank Arena at 7:30 p.m. EST.