The San Francisco 49ers can wrap up the NFC West with a win on Sunday against the Seattle Seahawks on Sunday Night Football. This is a big game because it will be the difference in going on the road for their first game of the playoffs or hosting it at Levi Stadium. So how are the 49ers going to perform?

Let's break down three bold predictions for the 49ers in their Week 17 game against the Seahawks.

3. 49ers have two different players over 75 yards rushing

Overall, the Seahawks' defense has been a big weakness this season and their inability to stop the run has been a big reason why. The 49ers should be able to take advantage of that with their pack of running backs.

The 49ers use a running back by committee approach and the last couple of weeks it has been Raheem Mostert and Tevin Coleman getting the most run.

Against the Los Angeles Rams, Mostert finished with 53 yards and Coleman rushed for 33 yards. The 49ers should run wild all over the Seahawks defense.

Wide receiver Deebo Samuel is also going to finish with a run over 35 yards.

2. “Beast Mode” finishes with less than 25 yards rushing

Marshawn Lynch has been all the talk surrounding the Seahawks, but he is going to be basically a non-factor in this game. The 49ers' run defense has been stepping up as of late. In the 49ers' last game against the Rams, Todd Gurley only rushed for 48 yards in the game.

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San Francisco 49ers wide receiver Brandon Aiyuk next to 49ers general manager John Lynch and 49ers head coach Kyle Shanahan. Aiyuk has a speech bubble that says “Fire pick, can’t lie.”

Ben Strauss ·

Brandon Aiyuk and Deebo Samuel with blank jerseys and question mark in the middle of both jerseys. NFL Draft logo in the background

Angelo Guinhawa ·

GM John Schneider in the middle, Kris Jenkins, Cooper Beebe, Cedric Gray around him, and Seattle Seahawks wallpaper in the background

Enzo Flojo ·

The Seahawks are going to try and get Lynch established in this game, but it's not going to work out well. Look for Lynch to have at least 13 rushing attempts and for him to finish with under 25 yards rushing.

1. Jimmy G throws a pick-six, and it costs the 49ers the game

Jimmy Garoppolo has played pretty well this season, but there is still one area he is really struggling. That area would be turnovers. Against the Rams, he threw two interceptions and kept them closer than they probably should have been.

This is going to be a close game late and Jimmy G is going to try and play hero by making the big throw. That plan is going to backfire on him and it will result in a pick-six. The Seahawks will end up winning by seven points and the touchdown is going to be the difference with the 49ers going on the road to start their run for the Super Bowl.