| May 30 | @  | 12:10 AM | SCHN | Minute Maid Park |
| May 31 | @ | 12:10 AM | FDSSUN | Minute Maid Park |
| May 31 | @ | 8:10 PM | SCHN | Minute Maid Park |
| Jun 1 | @ | 6:10 PM | SCHN | Minute Maid Park |
| Jun 3 | vs.  | 11:35 PM | FDSSUN | Tropicana Field |
| Jun 4 | vs. | 11:35 PM | RSN | Tropicana Field |
| Jun 5 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Jun 6 | vs.  | 5:10 PM | FDSFL | Tropicana Field |
| Jun 7 | vs. | 8:10 PM | FDSSUN | Tropicana Field |
| Jun 8 | vs. | 4:10 PM | FDSSUN | Tropicana Field |
| Jun 9 | @  | 11:10 PM | FDSSUN | Fenway Park |
| Jun 10 | @ | 11:10 PM | NESN | Fenway Park |
| Jun 11 | @ | 11:10 PM | NESN | Fenway Park |
| Jun 13 | @  | 11:10 PM | SNY | Citi Field |
| Jun 14 | @ | 8:10 PM | SNY | Citi Field |
| Jun 15 | @ | 5:40 PM | WPIX | Citi Field |
| Jun 16 | vs.  | 11:35 PM | FDSSUN | Tropicana Field |
| Jun 17 | vs. | 11:35 PM | MASN2 | Tropicana Field |
| Jun 18 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Jun 19 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Jun 20 | vs.  | 11:05 PM | FDSSUN | Tropicana Field |
| Jun 21 | vs. | 4:10 PM | FDSSUN | Tropicana Field |
| Jun 22 | vs. | 4:10 PM | FDSSUN | Tropicana Field |
| Jun 24 | @  | 11:40 PM | FDSSUN | Kauffman Stadium |
| Jun 25 | @ | 11:40 PM | FDSSUN | Kauffman Stadium |
| Jun 26 | @ | 6:10 PM | FDSSUN | Kauffman Stadium |
| Jun 27 | @ | 11:05 PM | Apple TV+ | Oriole Park at Camden Yards |
| Jun 28 | @ | 8:05 PM | FDSSUN | Oriole Park at Camden Yards |
| Jun 29 | @ | 5:35 PM | FDSSUN | Oriole Park at Camden Yards |
| Jun 30 | vs.  | 11:35 PM | FDSSUN | Tropicana Field |
| Jul 1 | vs. | 11:05 PM | FDSSUN | Tropicana Field |
| Jul 2 | vs. | 4:10 PM | NBCS-CA | Tropicana Field |
| Jul 4 | @  | 8:10 PM | FDSSUN | Target Field |
| Jul 5 | @ | 6:10 PM | FDSSUN | Target Field |
| Jul 6 | @ | 6:10 PM | FDSSUN | Target Field |
| Jul 7 | @ | 10:40 PM | Fox Sports 1 | Comerica Park |
| Jul 8 | @ | 10:40 PM | FDSDET | Comerica Park |
| Jul 9 | @ | 5:10 PM | FDSDET | Comerica Park |
| Jul 10 | @ | 11:10 PM | FDSSUN | Fenway Park |
| Jul 11 | @ | 11:10 PM | NESN | Fenway Park |
| Jul 12 | @ | 8:10 PM | NESN | Fenway Park |
| Jul 13 | @ | 5:35 PM | FDSSUN | Fenway Park |
| Jul 18 | vs. | 11:35 PM | MASN2 | Tropicana Field |
| Jul 19 | vs. | 11:05 PM | FDSSUN | Tropicana Field |
| Jul 20 | vs. | 4:10 PM | MASN2 | Tropicana Field |
| Jul 21 | vs.  | 11:35 PM | FDSSUN | Tropicana Field |
| Jul 22 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Jul 23 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Jul 25 | @  | 11:10 PM | FDSSUN | Great American Ballpark |
| Jul 26 | @ | 10:40 PM | FDSSUN | Great American Ballpark |
| Jul 27 | @ | 5:40 PM | FDSOH | Great American Ballpark |
| Jul 28 | @  | 11:05 PM | YES | Yankee Stadium |
| Jul 29 | @ | 11:05 PM | YES | Yankee Stadium |
| Jul 30 | @ | 11:05 PM | FDSSUN | Yankee Stadium |
| Jul 31 | @ | 5:05 PM | YES | Yankee Stadium |
| Aug 1 | vs.  | 11:35 PM | FDSSUN | Tropicana Field |
| Aug 2 | vs. | 5:10 PM | SportsNet LA | Tropicana Field |
| Aug 3 | vs. | 4:10 PM | FDSSUN | Tropicana Field |
| Aug 5 | @  | 1:38 AM | FDSSUN | Angel Stadium of Anaheim |
| Aug 6 | @ | 1:38 AM | FDSSUN | Angel Stadium of Anaheim |
| Aug 6 | @ | 8:07 PM | FDSSUN | Angel Stadium of Anaheim |
| Aug 9 | @  | 1:40 AM | FDSSUN | T-Mobile Park |
| Aug 10 | @ | 1:40 AM | FDSSUN | T-Mobile Park |
| Aug 10 | @ | 8:10 PM | ROOT Sports NW | T-Mobile Park |
| Aug 12 | @ | 2:05 AM | NBCS-CA | RingCentral Coliseum |
| Aug 13 | @ | 2:05 AM | FDSSUN | RingCentral Coliseum |
| Aug 14 | @ | 2:05 AM | NBCS-CA | RingCentral Coliseum |
| Aug 16 | @  | 2:15 AM | NBCS-BA | Oracle Park |
| Aug 17 | @ | 1:05 AM | FDSSUN | Oracle Park |
| Aug 17 | @ | 8:05 PM | FDSSUN | Oracle Park |
| Aug 19 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Aug 20 | vs. | 11:35 PM | YES | Tropicana Field |
| Aug 21 | vs.  | 11:35 PM | FDSSUN | Tropicana Field |
| Aug 22 | vs. | 11:35 PM | FDSMW | Tropicana Field |
| Aug 24 | vs. | 4:10 PM | FDSMW | Tropicana Field |
| Aug 25 | @  | 10:40 PM | FDSSUN | Progressive Field |
| Aug 26 | @ | 10:40 PM | FDSSUN | Progressive Field |
| Aug 27 | @ | 5:10 PM | FDSSUN | Progressive Field |
| Aug 29 | @  | 10:45 PM | FDSSUN | Nationals Park |
| Aug 30 | @ | 8:05 PM | MASN | Nationals Park |
| Aug 31 | @ | 5:35 PM | FDSSUN | Nationals Park |
| Sep 1 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Sep 2 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Sep 3 | vs. | 11:35 PM | ROOT Sports NW | Tropicana Field |
| Sep 4 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Sep 5 | vs. | 11:35 PM | CLEG | Tropicana Field |
| Sep 6 | vs. | 11:05 PM | FDSSUN | Tropicana Field |
| Sep 7 | vs. | 4:10 PM | CLEG | Tropicana Field |
| Sep 9 | @ | 11:40 PM | CHSN | Guaranteed Rate Field |
| Sep 10 | @ | 11:40 PM | CHSN | Guaranteed Rate Field |
| Sep 11 | @ | 6:10 PM | FDSSUN | Guaranteed Rate Field |
| Sep 12 | @  | 6:20 PM | FDSSUN | Wrigley Field |
| Sep 13 | @ | 6:20 PM | MARQ | Wrigley Field |
| Sep 14 | @ | 6:20 PM | FDSSUN | Wrigley Field |
| Sep 15 | vs.  | 11:35 PM | SNET | Tropicana Field |
| Sep 16 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Sep 17 | vs. | 11:05 PM | FDSSUN | Tropicana Field |
| Sep 18 | vs. | 5:10 PM | SNET | Tropicana Field |
| Sep 19 | vs. | 11:35 PM | FDSSUN | Tropicana Field |
| Sep 20 | vs. | 11:05 PM | FDSSUN | Tropicana Field |
| Sep 21 | vs. | 4:10 PM | NESN | Tropicana Field |
| Sep 23 | @ | 10:35 PM | MASN2 | Oriole Park at Camden Yards |
| Sep 24 | @ | 10:35 PM | FDSSUN | Oriole Park at Camden Yards |
| Sep 25 | @ | 5:05 PM | FDSSUN | Oriole Park at Camden Yards |
| Sep 26 | @ | 11:07 PM | SNET | Rogers Centre |
| Sep 27 | @ | 7:07 PM | FDSSUN | Rogers Centre |
| Sep 28 | @ | 7:07 PM | FDSSUN | Rogers Centre |
