| Aug 10 | @  | 12:30 AM | | Levi's Stadium |
| Aug 17 | vs.  | 1:30 AM | NFL Network | Empower Field at Mile High |
| Aug 23 | @  | 5:00 PM | | Caesars Superdome |
| Sep 7 | vs.  | 8:05 PM | FOX | Empower Field at Mile High |
| Sep 14 | @  | 8:05 PM | CBS | Lucas Oil Stadium |
| Sep 21 | @  | 8:05 PM | CBS | SoFi Stadium |
| Sep 30 | vs.  | 12:15 AM | ABC | Empower Field at Mile High |
| Oct 5 | @  | 5:00 PM | CBS | Lincoln Financial Field |
| Oct 12 | @  | 1:30 PM | NFL Network | MetLife Stadium |
| Oct 19 | vs.  | 8:05 PM | CBS | Empower Field at Mile High |
| Oct 26 | vs.  | 8:25 PM | CBS | Empower Field at Mile High |
| Nov 2 | @  | 6:00 PM | FOX | NRG Stadium |
| Nov 7 | vs.  | 1:15 AM | Amazon Prime Video | Empower Field at Mile High |
| Nov 16 | vs.  | 9:25 PM | CBS | Empower Field at Mile High |
| Dec 1 | @  | 1:20 AM | NBC | FedExField |
| Dec 7 | @ | 9:05 PM | CBS | Allegiant Stadium |
| Dec 14 | vs.  | 9:25 PM | CBS | Empower Field at Mile High |
| Dec 21 | vs.  | 9:05 PM | FOX | Empower Field at Mile High |
| Dec 26 | @ | 1:15 AM | Amazon Prime Video | GEHA Field at Arrowhead Stadium |
| Jan 4 | vs. | 6:00 PM | | Empower Field at Mile High |
