DeAndre Hopkins has gotten off to a blazing start with the Arizona Cardinals, but it remains to be seen if he suits up in Week 4. After Arizona's devastating loss to the Detroit Lions in Week 3, Hopkins missed practice on Wednesday, making it uncertain if he'll play versus the Carolina Panthers on Sunday.

Hopkins was unable to practice on Wednesday due to an ankle injury. It remains to be seen exactly when Hopkins suffered the injury, and it is unknown what the extent of the injury is.

In his first three games with the Cardinals, Hopkins showed off his chemistry with Kyler Murray. The All-Pro wideout has totaled 32 receptions for 356 yards and one touchdown so far this season.

Given that, Hopkins is on pace to finish with 170 receptions for 1,898 yards in his inaugural season with the Cardinals. If he were to conclude the season with 170 receptions, he would smash the single-season record of 149 catches set by Michael Thomas in 2019.

Throughout his career, Hopkins has been able to stay healthy, missing just two games in his first seven seasons in the NFL. Even though he missed practice, it's too early to assume what his designation will be for Sunday's game versus the Panthers.

The Panthers, under new head coach Matt Rhule, have allowed 258.3 passing yards per game this season (ninth-most in the NFL). If Hopkins is able to suit up on Sunday, he's poised to have another productive outing in Week 4. At the same time, if his ankle injury continues to bother him, then Christian Kirk and Andy Isabella could see expanded roles in the offense.