The Arizona Cardinals Week 16 matchup against the Indianapolis Colts is one of the most important contests for both franchises this year. Both teams are fighting for playoff positioning and a victory would be massive while a loss could be detrimental. We take a look at this Cardinals-Colts game with some of our Cardinals Week 16 predictions in mind.
Arizona's defense has played much better than expected. Even so, they're going against a Colts team who have been lights out recently. This is a tough matchup for the Cardinals, but their defense is capable of keeping up with Indianapolis. Look for Arizona to do everything possible to make Carson Wentz uncomfortable on Saturday.
For more insight on the Cardinals' Week 16 matchup against the Colts, listen below:
Offensively, the Cardinals could use a boost. For whatever reason, this team has looked flat in their last two games. It's time for them to turn it around and prove to the league they're true contenders. For that to happen, we need to see Chase Edmonds produce solid numbers, while Kyler Murray has a massive bounce-back performance. If that happens, Arizona should be able to pull out a win.
With that said, here are four bold Cardinals Week 16 predictions for their game against the Colts.
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Cardinals Week 16 Predictions
4. Arizona's defense forces 3 turnovers
The Colts' offense starts and ends with Jonathan Taylor. There won't be much for the Cardinals to do to slow him down. Therefore, Arizona should focus on pressuring Carson Wentz on Saturday. He's shown improvement this season, but Wentz has a knack for making terrible decisions when defenders are in his face.
For that reason, the Cardinals' pass rush must be on point. The best strategy is to force the Colts into third and long situations, then bring the heat. With injuries and COVID derailing the Indianapolis offensive line, there's a real chance Arizona can pressure Wentz significantly and force multiple turnovers.
3. Chase Edmonds goes off for 100+ total yards and 2 touchdowns
Chase Edmonds wasn't at his best in his return to the lineup in Week 15. However, he's had enough time to get fully acquainted with his offense once again. With James Conner questionable to play, the Cardinals need Edmonds to step up against the Colts. Indianapolis has a tough defense, but Edmonds can take advantage of them in the passing game.
2. Kyler Murray bounces back with a big performance
It's been ugly for Kyler Murray lately, but he's bound to bounce back sooner or later. With the playoff race being so close this season, the Cardinals need their star quarterback to be at his best. Murray has the ability to take any game over, and that's exactly what Arizona needs him to do on Christmas Day.
1. Cardinals earn a massive win over Indianapolis
It's time for the Cardinals to get back to their winning ways. This is the perfect matchup for Arizona to prove to the league they have what it takes to be a contender. This team needs everything to come together, as the Colts are a solid team throughout.
If Arizona's defense can force turnovers, while the offense bounces back, the Cardinals will be able to lock up another win. All eyes will be on Kyler Murray, as he's the leader of this organization. This game is likely to come down to the wire, but Arizona has the tools necessary to defeat the Colts on Saturday.
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