Indiana Pacers big man Myles Turner is now being listed as week-to-week with a sprained right ankle, according to a report from Shams Charania of The Athletic.

Turner, now 23 year of age, suffered the ankle injury in the first quarter of Wednesday night's 118-108 victory over the Brooklyn Nets and did not return. He's expected to undergo an MRI exam, and he'll be held out of Friday night's matchup against the Cleveland Cavaliers. He's likely to miss at least a few games due to the injury.

This is obviously a tough blow for the Pacers, as Turner has a big presence in the paint. Through his first four appearances with the team this season, the former No. 11 overall pick has racked up averages of 14.8 points on 55.0 percent shooting from the field (53.3 percent from beyond the arc), 6.8 rebounds and 1.3 blocks in 31.5 minutes per outing.

With Turner out, Domantas Sabonis and Goga Bitadze will likely see an uptick in their usage rates. Justin Holiday could also see a bit more playing time.

Via ESPN:

“It's tough,” Sabonis said about losing Turner. “Because it's the beginning of the season, we're also trying to find each other and find that chemistry and play together, and obviously he's going to be out for a little bit. It's tough. I wish him a speedy recovery. When he comes back he's going to help us, he's the best defender in the league.”

Friday night's matchup between the Pacers and Cavs is set to tip inside Bankers Life Filedhouse at 7:00 p.m. ET.

Hopefully, Turner will be able to recover sooner rather than later.