The New England Patriots will be without one of their top defensive players on Sunday against the Buffalo Bills. According to Field Yates of ESPN, Patriots cornerback Stephon Gilmore has been ruled out due to a knee injury.

Gilmore was reportedly involved in a collision in practice on Thursday and was a limited participant that day. According to Ian Rapoport of NFL Network, the knee injury was deemed minor; however, the 30-year-old cornerback didn't practice on Friday and was officially ruled out on Saturday. With Gilmore's absence, the Patriots are expected to start third-year player J.C. Jackson in Sunday's game against the Bills. He was also limited in practice on Friday with knee soreness, but he's expected to be ready to go on Sunday.

Neverthless, Gilmore isn't the only player that will miss the game on Sunday. Patriots receiver Julian Edelman is also expected to be out due to a knee injury he suffered last week. In addition to Edelman, N'Keal Harry will also be out due to a concussion he suffered in last week's loss against the San Francisco 49ers.

These injuries come at a bad time for the Patriots as they face the Bills, who are the top team in the division. The Patriots, who currently own a record of 2-4, are 2.5 games behind the Bills, so this game will be crucial for them. If the Patriots don't win the division, it'll be tough for them to make the playoffs, considering how competitive the wild card spots are in the AFC.