The Cleveland Guardians will continue their opening weekend series with the Seattle Mariners in a Friday night MLB matchup at T-Mobile Park in Seattle. With that said, it’s a good time to check out our MLB odds series, which includes a Guardians-Mariners prediction and pick, laid out below.

Cleveland won the AL Central with a 92-70 record last season. With the lowest record amongst the division winners, Cleveland faced off with the Tampa Bay Rays in the Wild Card series, which they won before losing in five games to the New York Yankees in the ALDS.

Seattle earned a playoff berth in 2022 for the first time since 2001 with a 90-72 record. Seattle defeated Toronto in the Wild Card series before being swept in three games against the Houston Astros. Seattle won their Opening Day matchup against Cleveland.

Here are the Guardians-Mariners MLB odds, courtesy of FanDuel. 

MLB Odds: Guardians-Mariners Odds

Cleveland Guardians: +1.5 (-156)

Seattle Mariners: -1.5 (+130)

Over: 7.5 (-122)

Under: 7.5 (+100)

How To Watch Guardians vs. Mariners

TV: Bally Sports Great Lakes, ROOT Northwest

Stream: MLB.tv

Time: 10:10 PM ET/7:10 PM PT

*Watch MLB games LIVE with fuboTV (click for a free trial)*

Why The Guardians Could Cover The Spread

Jose Ramirez finished fourth in the AL MVP voting last season after slashing .280/.355/.514 with 44 doubles and 29 home runs, while stealing 20 bases. Ramirez led the American League in doubles, and has shown no signs of slowing down his reign over opposing pitching. Josh Bell was a big offseason addition to the Cleveland lineup, splitting time with Washington and San Diego last season. Bell hit 29 doubles and 17 home runs, winning the National League Silver Slugger at DH.

Andres Gimenez signed a huge contract extension just before the season began, rewarded after a career year in which he hit 26 doubles, 17 home runs, stole 20 bases and earned his first All-Star berth and Gold Glove. Steven Kwan also won a Gold Glove in his rookie season, while also hitting .298 with 25 doubles and more walks than strikeouts.

Hunter Gaddis made a brief cameo at the end of last season, struggling in two starts. Gaddis owns a 3.90 ERA in his minor league career, earning praise for his slider and changeup. Cleveland's strong bullpen is headlined by Trevor Stephan, who also received a contract extension before Opening Day. Stephan pitched to a 2.69 ERA with 82 strikeouts in 63.2 innings. Closer Emmanuel Clase is nearly unhittable, with a career 1.47 ERA thanks to his triple digits cutter.

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Why The Mariners Could Cover The Spread

Julio Rodriguez debuted with tons of fan fare last season, and delivered on all of it, winning the AL Rookie of the Year with a .284/.345/.509 slash, hitting 28 home runs and stealing 25 bases. Rodriguez also was named a Silver Slugger and finished seventh in AL MVP voting. Teoscar Hernandez was acquired from Toronto in the offseason, bringing an added punch to the lineup. Hernandez hit 35 doubles and 25 home runs last season.

JP Crawford has taken a step forward as a hitter in the last two seasons, hitting 61 doubles combined in those two years. Catcher Cal Raleigh belted 27 home runs while providing solid defense last season. Ty France belted a huge three-run home run in the Guardians-Mariners opener after hitting 20 home runs last season.

Robbie Ray will make his first start of the season in this one. Ray was solid in his first season with Seattle, pitching to a 3.71 ERA with 212 strikeouts in 189.0 innings. Matt Brash has displayed a bit of an uptick in stuff since his shift to the bullpen, with a career 2.27 ERA and 45 strikeouts in 31.2 innings out of the bullpen. Closer Paul Sewald was dominant last season, striking out 72 batters in 64.0 innings, totaling 20 saves.

Final Guardians-Mariners Prediction & Pick

Seattle will take advantage of the inexperienced Gaddis in this one.

Final Guardians-Mariners Prediction & Pick: Seattle -1.5 (+130), over 7.5 (-122)