Stefanos Tsitsipas suffered a stunning loss to American Francis Tiafoe in Wimbledon just weeks after his French Open collapse against Novak Djokovic.

Tsitsipas entered Wimbledon as one of the favorites in the men's draw after he blew a two-set lead to Djokovic in the final of the French Open. However, his tournament came to a shocking end Monday after Tiafoe defeated him in straight sets.

Tiafoe moved on to the second round of Wimbledon after a 6-4, 6-4, 6-3 victory over Tsitsipas that will surely have massive implications for the rest of the men's draw.

It's been a difficult stretch for Tsitsipas. The Greek star looked to be on the cusp of his first major championship in Paris after dominating Djokovic through the first couple sets of the French Open final. However, the resilient Djokovic battled back to win each of the next three sets.

A heartbroken Tsitsipas revealed after that match he learned of his grandmother's death a mere five minutes before taking the court:

“I would like to say that regardless of the day, circumstance or situation, this is entirely dedicated to her, and only her,” Tsitsipas said, via the Washington Post. “Thank you for raising my father. Without him this wouldn’t have been possible.”

Tsitsipas seemed as strong a candidate as any to win on the grass courts at Wimbledon. Instead, it's Tiafoe who will be hoping to make an underdog run at The Championships. Tiafoe will face the winner of the first-round match between Robert Carballes Baena and Vasek Pospisil.

Meanwhile, this is yet another top contender no longer in the draw as Djokovic hopes to capture another Wimbledon title. The Serbian star has already captured the first two Grand Slam tournaments of the year and will be hoping to win again at The Championships.