The San Francisco 49ers host the New York Jets in Week 1 on Monday Night Football. 49ers running back Christian McCaffrey has been dealing with a calf strain during the preseason and was initially listed as questionable for Monday's game. McCaffrey's injury is officially listed as a calf and Achilles injury and he's been practicing in a limited capacity all week, according to Ian Rapoport of NFL Network.

Here's everything we know about Christian McCaffrey's injury and his playing status vs. the Jets.

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Christian McCaffrey injury status vs. Jets

San Francisco 49ers running back Christian McCaffrey (23) against the Arizona Cardinals at State Farm Stadium.
Mark J. Rebilas-Imagn Images

Prior to the start of the Week 1 showdown, Christian McCaffrey has been downgraded to out, per Mike Garafolo of NFL Network.

The 49ers and the Jets are matching up in what is one of the most highly-anticipated Week 1 games on this NFL slate. The 49ers are one of the favorites to make it out of the NFC once again, and are trying to finally get over that Super Bowl hump after coming so close so many times in recent years. Optimism is abound about the Jets, who will have Aaron Rodgers back after tearing his Achilles in Week 1 last season. The Jets' defense has all the makings of an elite unit as well, so this should be a fascinating clash.

As for McCaffrey, he changes the calculus of the defense whenever he is on the field. Kyle Shanahan has figured out how to unlock and weaponize McCaffrey's versatile skillset as one of the best runners and receivers in football, and that makes him nearly impossible to stop. Shanahan will line McCaffrey up just about anywhere: at running back, in the slot, or on the outside to create advantages matchups and leverage. Last season, McCaffrey racked up 2,023 yards from scrimmage and 21 touchdowns and won the NFL's Offensive Player of the Year award.

McCaffrey missed just one game in 2023 when he sat out of the 49ers' Week 18 game with the Rams due to rest after the 49ers clinched the No. 1 seed.

When it comes to the question if Christian McCaffrey is playing tonight against the Jets, unfortunately, the answer is no.