San Francisco 49ers quarterback will be without one weapon downfield when they go up against the Detroit Lions on Sunday. According to Cam Inman of the San Jose Mercury News, the 49ers will face the Lions minus wide receiver Marquise Goodwin due to a quad injury.

This is hardly a surprise anymore, as Goodwin hasn’t practiced since Week 1’s 24-16 loss to the Minnesota Vikings on the road. In that game, Goodwin barely made his presence felt, as he failed to pull down a catch on only one target. He exited the game in the second quarter after banging bodies with Minnesota defensive tackle Jaleel Johnson. Goodwin returned later in the contest, but did not factor much in San Francisco’s passing attack.

The 49ers’ offense is already missing running back Jerick McKinnon, who is out for the season because of an ACL tear. With Marquise Goodwin also out for at least the second week of the season, San Francisco’s character and the ability of head coach Kyle Shanahan to lead an undermanned squad is being put to test early.

Goodwin’s absence means that rookie Dante Pettis will see an increased workload against the Lions. Last week, the 49ers’ second-round pick in this year’s NFL Draft made a solid pro debut, as he caught two passes and converted them into 61 receiving yards and a touchdown.

Dating back to 1996, the 49ers are 9-1 in their last 10 meetings with Detroit.