If things couldn't get worse for the Cavs, they have an injury concern to worry about with star guard Donovan Mitchell during their Game 4 matchup against the Indiana Pacers on Sunday night.

Mitchell and the Cavs were unable to contain the Pacers' offense in the first half. They went down early, trailing 38-23 after the first quarter. It got worse in the next 12 minutes as Indiana went on a 19-2 run to grow their lead to 80-39 at halftime.

Mitchell was preparing for the second half when he appeared to be suffering through pain around the lower body. He left the court during warmups as he made his way to the locker room.

He stayed as the Cavs and Pacers started play for the second half. It took a while until midway through the third quarter, when the team revealed he has a left ankle injury. He initially was doubtful until Cleveland later ruled him out for the remainder of the contest.

Mitchell will end the night with 12 points, a rebound and a steal after 20 minutes of play.

How Cavs played after Donovan Mitchell's exit

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Donovan Mitchell's exit from the game with the injury sealed the deal as the Cavs lost in a 129-109 blowout to the Pacers in Game 5.

They reduced the deficit Indiana had on them, winning the third and fourth quarters. However, it wasn't enough as the gap was too big to overcome as the Pacers were on cruise control throughout the last 24 minutes.

Six players scored in double-digits on Cleveland's behalf in the loss, including Mitchell. Darius Garland led the way with 21 points, six assists, a rebound, and a steal. He shot 6-of-11 from the field, including 1-of-5 from downtown, and 8-of-8 from the free-throw line. Isaac Okoro came next with 13 points and two rebounds, Max Strus put up 11 points and six rebounds, while Jaylon Tyson provided 11 points and three assists.

The Cavs will look to stay alive in the series when they host the Pacers in Game 5. The contest will take place on May 13 at 7 p.m. ET.