The Purdue Boilermakers (0-1) travel to Blacksburg to take on the Virginia Tech Hokies (1-0). This game will continue our college football odds series as we hand out a Purdue-Virginia Tech prediction and pick. We will also let you know how to watch the game.

Purdue is coming off a disappointing loss against Fresno State last week. They took the lead late in the fourth quarter, but with a minute left, Fresno State scored the game winning touchdown. Despite Purdue's poor defensive showing, their offense came to play. They gained over 360 yards of total offense, and they did through the air and on the ground. Hudson Card threw for 254 yards and two touchdowns while Devin Mockobee rushed for 60 yards and a touchdown. Deion Burks made the most of his receptions as he had four catches for 152 yards and two touchdowns in the game. The defense will need to play better against Virginia Tech, though.

Virginia Tech is coming off a home win against Old Dominion. Grant Wells passed for 251 yards and three touchdowns to lead the Hokies to victory in the game. Wells also had 27 rushing yards, and scored the only rushing touchdown for Virginia Tech. Ali Jennings had two of the three touchdowns at wide receiver while Jaylin Lane caught the other. Virginia Tech was relentless on defense, as well. They had nine tackles for a loss, five sacks, and an interception. The Hokies did what they should have against a worse team, but the matchup with Purdue will be a little bit tougher.

Here are the college football odds, courtesy of FanDuel. 

College Football Odds: Purdue-Virginia Tech Odds

Purdue: +2.5 (-112)

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Virginia Tech: -2.5 (-108)

Over: 49.5 (-110)

Under: 49.5 (-110)

How to Watch Purdue vs. Virginia Tech


Stream: ESPN app

Time: 12 PM ET/9 AM PT

*Watch college football LIVE with fuboTV (click for a free trial)*

Why Purdue Will Cover The Spread

Purdue needs to pick it up on defense. Wells had a good game in week one, but Purdue is not Old Dominion. Virginia Tech is going to struggle a little more in this game, and Purdue needs to take advantage defensively. Wells only completed 58 percent of his passes, and it seemed like he was not scared to use his legs. If Purdue can put the pressure on Wells in the pocket, he will make some mistakes. Wells is a better passer than a runner, so Purdue needs to force him to make some bad throws. Doing this will cause some turnovers, but also keep Virginia Tech's drives short.

Offensively, Purdue should keep doing what they have been doing. They scored 35 points against Fresno State, so their offense was not the problem. Cards was just okay through the air, so he needs to pick it up a little bit. Virginia Tech's defense will come into this game with a lot of confidence, so Purdue needs to be ready for that. Virginia Tech did give up over 200 rush yards against ODU, so Purdue could use that to their advantage. If they can get the run game going, it will open up a lot for the pass game.

Why Virginia Tech Will Cover The Spread

Virginia Tech, as mentioned, will come into this game with a lot of confidence on the defensive side of the ball. The pressure they put on ODU in the passing game was a very positive sign for the Hokies. They will need to do the same in this game. Purdue is a better team when their pass game is working. If Virginia Tech can crowd the pocket, force some mistakes, and continue playing well in pass coverage, they should cover the spread. Forcing Purdue to run the ball is going to be key in this game.

Offensively, the Hokies should not have much problem. Purdue was very bad in week one, and it does not get any easier against Virginia Tech. Wells and Ali Jennings should be able to get on the same page once again and get the ball in the endzone. Purdue did not get much pressure on the quarterback during week one, so Wells will have plenty of time to read the defense and make the right throw.

Final Purdue-Virginia Tech Prediction & Pick

This game will end up being close. They are two middle-of-the-pack college football teams, and it will show in this game. When it comes down to it, it is very hard to win on the road against a power-5 team. I will take Virginia Tech in this game.

Final Purdue-Virginia Tech Prediction & Pick: Virginia Tech -2.5 (-108), Over 49.5 (-110)