The Astros make the trip to Chicago to face the White Sox! These two teams are very different this year with the Astros being inconsistent, while the White Sox are the worst team in the MLB. Both teams come into this series having trouble with recent consistency. Our MLB odds series has our Astros-White Sox prediction, odds, and pick for Wednesday.

Astros-White Sox Projected Starters 

Hunter Brown vs. Garrett Crochet

Hunter Brown (3-5) with a 5.00 ERA and a 1.43 WHIP

Last Start: Pitched seven innings and gave up zero runs and five hits with zero walks and nine strikeouts in an Astros win.

2024 Road Splits: (1-3) 6.93 ERA

Garrett Crochet (6-5) with a 3.16 ERA and a 0.90 WHIP

Last Start: Pitched seven innings and gave up one run on two hits with two walks and 13 strikeouts in a White Sox win.

2024 Home Splits: (4-3) 2.36 ERA

Here are the MLB Odds, courtesy of FanDuel. 

MLB Odds: Astros-White Sox Odds

Houston Astros: -1.5 (+146)

Moneyline: -120

Chicago White Sox: +1.5 (-176)

Moneyline: +102

Over: 7.5 (+102)

Under: 7.5 (-124)

How to Watch Astros vs. White Sox

Time: 8:10 pm ET

TV: Space City Home Network / NBC Sports Chicago

Stream: fuboTV (Click for free trial)

Why The Astros Will Cover The Spread/Win

The Astros have opened this season struggling. They have a 33-39 record and they have struggled to find any consistency this season. Despite their struggles, their offense has been great this season with the second-best batting average in the MLB. Jose Altuve, Kyle Tucker, Jeremy Pena, Yainer Diaz, and Yordan Alvarez have been great for Houston behind the plate. The issue is all on the mound where they have struggled. Ronel Blanco, Framber Valdez, and Justin Verlander have stood out on a struggling staff. The Astros have talent, but they have not been able to find any consistency.

The Astros are starting Hunter Brown on the mound. He has a 3-5 record, a 5.00 ERA, and a 1.43 WHIP. Brown has allowed 39 runs on 69 hits with 29 walks and 76 strikeouts through 68.1 innings up to this point in the season. In his 14 appearances for Houston this season, the Astros are 4-10. Brown has struggled this season, but he gets a favorable matchup against the White Sox and their offense. He has played better recently, so that works in his favor against an offense as bad as the White Sox.

The offense for the Astros has been the second-best in the MLB so far this season. They are second in batting average at .258 after they finished last season at .259. Jose Altuve and Kyle Tucker lead the Astros in almost every important batting category. Tucker leads in home runs at 19, in RBI at 40, and in OBP at .395. Then, Altuve leads the way in batting average at .299 and in total hits at 87. The Astros have been great on offense, but they get a difficult matchup against the best pitcher for the White Sox Garrett Crochet on the mound.

Why The White Sox Will Cover The Spread/Win

The White Sox are the worst team in the MLB currently. They have a 19-54 record so far this season. They are tied for being the worst team in the MLB behind the plate and are also struggling on the mound, ranking second to last, and are only in front of the Rockies. Gavin Sheets, Paul DeJong, Andrew Vaughn, and Andrew Benintendi are standouts despite how bad the offense has been. The only notable pitchers in the lineup are Erick Fedde and Garrett Crochet.

The White Sox are starting Garrett Crochet on the mound in this matchup and he has a 6-5 record, a 3.16 ERA, and a 0.90 WHIP. He has allowed 30 runs on 55 hits with 19 walks and 116 strikeouts. In his 15 starts this season, the White Sox are 7-8. Crochet has been one of the few bright spots for the White Sox this season on the mound, but he gets a difficult matchup against the offense from the Astros behind the plate.

The offense for the White Sox has been awful. The White Sox are tied for last in the MLB in team batting average at .220 which comes after having a .238 last season. Gavin Sheets, Paul DeJong, and Andrew Vaughn lead the offense in most categories. DeJong leads in batting average at .240 and in home runs at 14. Vaughn leads in RBI at 31 and in hits at 60. Finally, Sheets leads in OBP at .340. This is a favorable matchup for an offense that has struggled as much as the White Sox. Brown has struggled overall but has played recently in his two most recent starts.

Final Astros-White Sox Prediction & Pick

The White Sox have the pitching advantage in this game with Crochet over Brown for Houston. He is the X-factor because the offense for the Astros is head and shoulders better than the White Sox. The key is Crochet and how red-hot he has been. Expect the White Sox to cover and potentially win at home against the Astros.

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Final Astros-White Sox Prediction & Pick: White Sox +1.5 (-176)