NFL Week 5 Predictions, Josh Allen, Patrick Mahomes

2021 NFL Week 5 Predictions: Upset picks, betting locks, and more

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Blake Lovell and Dillon Reagan make their predictions for Week 5 of the 2021 NFL season, including their game of the week (a rematch of last season's AFC Championship game between the Kansas City Chiefs and Buffalo Bills should deliver another classic on Sunday Night Football), betting locks of the week (Blake looks to improve his record to 4-1 by locking up the Arizona Cardinals (-5) over the San Francisco 49ers, while Dillon tries to remain undefeated with his locks by picking the Baltimore Ravens (-7) to cover as they host the Indianapolis Colts on Monday night), and upsets of the week (Taylor Heinicke and the Washington Football Team look to build off last week's thrilling win as they host the New Orleans Saints, while Josh Allen and the Bills look for revenge over Patrick Mahomes in Kansas City).

The Establish the Pass podcast will return early next week to review all of the action from Week 5 and look forward with waiver wire pickup recommendations for Week 6.

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NFL Week 5 Predictions:

MatchupBlakeDillon
LAR @ SEASeahawksRams
NYJ @ ATLFalconsFalcons
DET @ MINVikingsVikings
NO @ WSHWashingtonSaints
NE @ HOUPatriotsPatriots
MIA @ TBBuccaneersBuccaneers
GB @ CINPackersPackers
DEN @ PITSteelersBroncos
PHI @ CARPanthersPanthers
TEN @ JAXTitansTitans
CLE @ LACChargersChargers
CHI @ LVRaidersRaiders
SF @ ARICardinalsCardinals
NYG @ DALCowboysCowboys
BUF @ KCChiefsBills
IND @ BALRavensRavens
Record36-2840-24

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For our Fantasy Football Start ‘Em Sit ‘Em recommendations for Week 5, click here.

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