The San Francisco 49ers could potentially be without quarterback C.J. Beathard for their Thursday Night Football clash against the Oakland Raiders due to a wrist injury, per Adam Schefter of ESPN.

As a source told Schefter, Beathard is apparently having a hard time gripping a football, which is a big reason why his status to play is “truly 50-50.”

If Beathard is not able to go, third-string QB Nick Mullens would be in line to start for the Niners. The 23-year-old went undrafted last year and has yet to play a single snap in the NFL.

Beathard has started the past five games after Jimmy Garoppolo went down with his season-ending knee injury. Beathard has completed 60 percent of his passes for 1,252 yards with eight touchdowns and seven interceptions in those five games, which the 49ers have all lost.

Beathard’s loss would be another huge blow to a 49ers offense which has struggled mightily after Garoppolo went down. They’ve been particularly impotent over the last two games, where they combined for just 25 points in losses to the Rams and Cardinals.

Beathard was pretty bad in both of those games as he completed just 52 percent of his passes for 360 yards with two touchdowns and two interceptions. Their running game hasn't been much better, especially with Matt Breida playing at less than 100 percent due to a nagging ankle injury.

But as bad as Beathard has been, it seems unlikely that the inexperienced Muller will be much better, which doesn’t bode well for the 49ers’ chances of snapping their six-game losing skid against the Raiders.