Duke and Florida State play on Tuesday night. It's time to continue our college basketball odds series with a Duke-Florida State prediction and pick.

Duke and Florida State will meet for the first time this season on Tuesday night. The Blue Devils come into play in this one as the No. 6 ranked team in the country with a 14-2 record. Florida State comes in at 10-5 but has won four of their last five games, which have all been vs. ACC opponents. Paolo Banchero continues to lead Duke this season as the freshman has became one of the best players in college basketball in a very short amount of time. Duke comes into this matchup as road favorites vs. Florida State on Tuesday night.

Here are the Duke-Florida State odds for Tuesday night, courtesy of FanDuel.

College Basketball Odds: Duke-Florida State Odds

Duke -5 (-110)

Florida State +5 (-110)

Over 145 (-120)

Under 145 (-102)

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Why Duke Could Cover The Spread

Duke has won two in a row after losing to Miami earlier this month, and will look to continue their streak on Tuesday vs. Florida State. Banchero continues to light up opponents as he's averaging 18 points and 7 rebounds per game this season while shooting above 50% from the floor. Florida State will be a tough opponent however as they have won four of their last five ACC games. The Blue Devils will need to bring a complete effort on Tuesday if they want to cover and win on the road.

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Duke vs. the spread

The Blue Devils are 9-5-2 vs. the spread this season so far. Duke is 8-5-2 as the favorite this season, and 1-1 vs. the spread as an away favorite.

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Why Florida State Could Cover The Spread

Florida State will look to stay hot in ACC play in this one. Leonard Hamilton seems to always put together a good team. After a slow start, it appears he has done that in Tallahassee again this season. The Seminoles have won four of their last five conference games and look primed to peak at the right time, right in the thick of the ACC schedule. Florida state is an appealing play as home underdogs vs. Duke on Tuesday, but be wary of a letdown.

Florida State vs. the spread

The Seminoles are 6-9 overall against the spread this season, covering in just three of their last ten games. Florida State is 1-0 as a home underdog so far this season, and 1-2 overall as an underdog coming into this one.

Final Duke-Florida State Prediction & Pick

Take the Seminoles to cover in this spot at home. Florida State has been hot lately, but they have not faced the level of competition that the Blue Devils bring to the table. They have the length to slow down Banchero, though he should be the best player on the floor. Duke may win in this spot, but Florida State and the points feels like the safe bet on Tuesday night.

Final Duke-Florida State Prediction & Pick: Florida State +5 (-110)