The Portland Trail Blazers and Los Angeles Clippers will play in an inter-conference matchup on Tuesday night. It's time to continue our NBA odds series and make a Blazers-Clippers prediction and pick.

The Blazers and Clippers will meet for the third time already this season. The two teams are 1-1 across those two matchups. The Clippers come in on a four-game win streak after a 1-4 start to the season. Portland has won their last two games after a three-game skid before that. The Blazers will look to get above .500 on Tuesday, as they are 5-5 through 10 games this season. Los Angeles will look to continue to move their way up the ladder in the West in hopes that Kawhi Leonard can return at some point this season.

Here's how bookmakers have set the Blazers-Clippers odds for this Tuesday night matchup.

NBA Odds: Blazers-Clippers Odds

Portland Trail Blazers +2.5 (-110)

Los Angeles Clippers -2.5 (-11o)

Over 221.5 points (-110)

Under 221.5 points (-110)

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Why The Blazers Can Cover The Spread

Portland comes into play with the ninth best net rating in the NBA. Damian Lillard and CJ McCollum still make up one of the best backcourts in the NBA, and it's a backcourt that is far better than what the Clippers roll out. The Blazers are 4-6 against the spread this season, and being a slim underdog on the road vs. a hot Clippers team may be a tough spot to back Portland. The Blazers can cover and win on Tuesday, but they will need to play well as the Clippers come in as one of the hottest teams in the NBA. Portland comes into play with no injury designations.

Why The Clippers Can Cover The Spread

The Clippers have the fourth best net rating so far this season, and that ranking is powered by their defense, which ranks third. This could be a fast-paced game, as both the Clippers and Blazers rank in the top-10 in the NBA in pace. Paul George has helped carry Los Angeles comes into play on a four-game win streak, and will look to continue finding their chemistry in this matchup. The Clippers could be a nice play to cover this slim spread on their home floor, as they have the better advanced numbers between these two teams despite their injuries. Los Angeles will look for their fifth straight win and a leg up on the Blazers in the season series.

Final Blazers-Clippers Prediction & Pick

Take the over in this contest, as these teams are fairly evenly matched and both the Blazers and Clippers like to play a fast pace.

FINAL BLAZERS-CLIPPERS PREDICTION & PICK: Over 221.5 points (-110)