The New York Giants will take on the Philadelphia Eagles in the first NFC East matchup of Week 16. It's time to continue our NFL odds series and make a Giants-Eagles prediction and pick.

The Giants have had one of the most disappointing seasons in the entire league. This was supposed to be the year that quarterback Daniel Jones took a big step forward and led his team to a serviceable record, but instead here we are. The Giants are an abysmal 4-10, a record that marks another season with very few positives. Now they play a young, up-and-coming Eagles team that has a shot at the postseason. Philadelphia scored a massive Week 15 win against the Washington Football team, and another win here could place them in the last wild card seed in the NFC. There's plenty on the line for these division rivals, so let's get into the pick.

For more insight on the Giants-Eagles matchup in Week 16, listen below:

Here are the Giants-Eagles odds, courtesy of FanDuel.

NFL Odds: Giants-Eagles Odds

New York Giants: +10 (-110)

Philadelphia Eagles: -10 (-110)

Over: 40.5 (-110)

Under: 40.5 (-110)

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Why The Giants Could Cover The Spread

Because of their horrendous record, this Giants defense doesn't get the credit it deserves. New York has held three of their last four opponents to 21 points or less, including an impressive defensive showing against the Dallas Cowboys. The last time these teams played, the Eagles were held to seven points. Philadelphia quarterback Jalen Hurts tossed for 129 yards and three interceptions. Now Hurts may be facing this defense without two starting offensive linemen, as tackle Jordan Mailata and guard Landon Dickerson could both easily miss this game. It's unfair to expect New York to repeat their previous performance, but they should be able to put together something similar.

Usually playing at home is a good thing, but the opposite has been true for the Eagles this season, Philadelphia is a disappointing 2-4 when they play at Lincoln Financial Field this year, one of the worst home records in the NFL. The Giants have been decent against the spread when they play on the road, earning themselves a 3-4 record as an away team this season.

Why The Eagles Could Cover The Spread

Ever since their embarrassment at the hands of the Giants, the Eagles have been rolling offensively. Philly posted 33 points against the New York Jets and 27 points against the Washington Football Team, with both performances resulting in multiple-score wins. Now Jalen Hurts and the offense will get a shot to make up for their awful performance against New York, and that's exactly what they'll do. The Giants allow 244 passing yards per game and a 67% completion percentage to opposing passers, two very mediocre numbers. New York has also been ripped apart by opposing ground games, as they allow a whopping 125 rushing yards per game to go along with 4.4 yards per carry. Philadelphia should recover from their last outing and produce well offensively here.

Despite what their 7-7 record may suggest, the Eagles have been one of the better teams in the NFL against the spread. Philly has earned a 7-6-1 record ATS, which is good for the 11th-best record against the spread in the league. The Eagles are also 3-1-1 ATS when they enter the game as a favorite. The Giants, on the other hand, have been one of the worst teams in the NFL when it comes to covering the spread. They have a 6-8 record ATS and a 3-4 record against the spread as road underdogs.

Final Giants-Eagles Prediction & Pick

The Eagles will redeem themselves in this game. Take Philadelphia to finally defend their home turf and score a dominant win in this game.

Final Giants-Eagles Prediction & Pick: Philadelphia Eagles: -10 (-110)