Los Angeles Rams running back Darrell Henderson Jr. has been nursing a thigh injury lately. Henderson was active but didn't see the field in last week's win over the Jacksonville Jaguars. The Rams were dealt a tough blow on Henderson ahead of Week 14 against the Arizona Cardinals.

Ouch. Henderson, who practiced in a limited fashion on both Thursday and Friday, seemed to be trending towards playing in Week 14 on Monday night against the Cardinals.

Now, Henderson, who has ran for 648 yards and five touchdowns this year, has to test negative twice on Sunday and Monday as well as prove that his thigh injury is fully behind him. Certainly possible, but not likely. The Rams will have to turn to Sony Michel to lead their backfield once again in Week 14.

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Fortunately for Los Angeles, Michel has proven capable of leading the backfield in the absence of Henderson this season. Michel has 20-plus carries in two games this season, with both of those games coming without Henderson in the lineup.

The former New England Patriot running back ran for over 100 yards last week against the Jacksonville Jaguars and could be leaned on once again if the Rams opt to play keep-away against the Cardinals' high-octane offense.

Not having Darrell Henderson Jr is a huge blow for the Rams, though they seem to have the running back depth to compete in his absence.