San Francisco 49ers running back Raheem Mostert has hardly had reason to smile this season.

Mostert has made multiple trips to the Injured Reserve. He also suffered a high-ankle sprain on Sunday against the Dallas Cowboys.

Ian Rapoport of NFL Network reported the latest injury will likely end Mostert's season with just two games to go.

It is a bitter end to a year that actually started with some positivity.

Mostert had demanded a trade if the 49ers failed to give him a pay increase. The undrafted back was coming off a tremendous 2019 campaign during which he rushed for 772 yards on 5.6 yards per carry and also scored 10 total touchdowns. He felt his late-season heroics deserved a raise. San Francisco agreed.

The 49ers did not give Mostert an extension but instead restructured his contract to reflect a higher base salary. It only made sense, given Mostert looked like the featured back heading into the 2020 season.

Mostert earned every new penny through the first couple of weeks of the season. He tallied 151 yards from scrimmage and a touchdown in Week 1 before rushing eight times for 92 yards and a score in Week 2. But Mostert also left that Week 2 matchup with an MCL sprain.

The 28-year-old would return and put together a couple of decent games in Weeks 5 and 6, only to suffer a high-ankle sprain that landed him on the 49ers' IR once again.

Mostert has mostly been part of a committee since coming off of IR in Week 12, and now he will shut it down after another ankle injury.