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Clemson vs. Pittsburgh prediction, odds, pick and more

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The Clemson Tigers and Pittsburgh Panthers will play in an important ACC matchup on Saturday afternoon. It’s time continue our college football odds series with a Clemson-Pittsburgh prediction and pick.

Clemson and No. 23 Pittsburgh will play in a big ACC game on Saturday, as Pitt looks to stay undefeated in ACC play, while Clemson looks to keep their ACC Championship hopes alive. Pittsburgh quarterback Kenny Pickett has looked like one of the best players in the country so far in 2021, as has his teammate, wide receiver Jordan Addison. Clemson still has a lot of talent, but has struggled immensely offensively throughout the season.

Here’s how the bookmakers have set the Clemson-Pittsburgh odds:

College Football Odds: Clemson-Pittsburgh Odds

Clemson +3.5 (-124), +138 ML

Pittsburgh -3.5 (+102), -168 ML

Over 47.5 points (-115)

Under 47.5 points (-105)

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Why Clemson Could Cover The Spread

Clemson is still the deeper team, and has much more on the defensive side compared to Pittsburgh. They can present a tougher challenge than anything Pickett and Addison have seen so far this season. Quarterback D.J. Uiagalelei has held the offense back a bit to say the least, so the Tigers will need to run the ball well to keep up with Pitt’s passing attack. This number  probably surprises people with Clemson as an underdog, but Pickett has been that good and Uiagalelei has been that bad.

Justyn Ross is explosive for Clemson on the outside, and Uiagalelei will need too find a way to get him going if Clemson is going to keep up with Pitt’s offense and get the cover on Saturday afternoon.

Why Pittsburgh Could Cover The Spread

Pickett has 21 touchdowns and 1 interceptions on the season, with almost 2,000 passing yards through six games. He’s been a beast for the Panthers. The Sophomore WR Jordan Addison has 586 yards and nine receiving touchdowns through six games, which is also astonishing. Pittsburgh has a legitimately explosive offense that can put up points on anyone. Pickett and Addison give the Panthers a great shot to cover vs. Clemson at home on Saturday. Pittsburgh might be a little bit susceptible to the run vs. a bigger Clemson team, but if Uiagalelei, it will be difficult for the Tigers to run the football again this week as it has been all season.

Final Clemson-Pittsburgh Prediction & Pick

Pickett and the Pittsburgh offense are too tough to fade vs. a Clemson team that hasn’t score more than 21 points vs. a Power 5 opponent all season. Ride with Pittsburgh and their passing attack to get the win and the cover vs. Clemson at home on Saturday.

FINAL CLEMSON-PITTSBURGH PREDICTION & PICK: Pittsburgh -3.5 (+102)