The Indianapolis Colts will make their home debut on Sunday against the Atlanta Falcons, but they may be without one of their key contributors on offense. The Colts released their injury report on Friday with both T.Y. Hilton and Marlon Mack being listed as questionable, according to Josh Alper of Pro Football Talk.

Hilton has been limited in practice throughout the week with an injury to his quad. It's unknown when the speedy wide receiver sustained the injury, but after logging another day at practice on Friday, it'd be surprising to see him miss Sunday's game.

Throughout his eight-year career, Hilton has only been inactive in four games due to injuries. The veteran wide receiver has been vital to Indianapolis' offense, catching 12 passes for 130 yards and three touchdowns.

As for Mack, the Colts starting running back was able to complete a limited practice on Friday. Prior to Friday, Mack was absent from the first couple of practices this week with a calf injury.

With Mack as the starter again this season, the Colts currently have the second-best rushing offense in the NFL. The only team in the NFL who has had more success running the ball is the Baltimore Ravens.

Additionally, running back Jonathan Williams is considered to be questionable in Week 3. That leaves Nyheim Hines and Jordan Wilkins as the healthy options behind Mack.

On the defensive side of the ball, Indianapolis will be without defensive captain Darius Leonard against the Falcons. Just two weeks into the season, the Colts are beginning to have issues with injuries.